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One-Month Global Longitudinal Strain Identifies Patients Who Will Develop Pacing-Induced Left Ventricular Dysfunction over Time: The Pacing and Ventricular Dysfunction (PAVD) Study

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  • Fozia Zahir Ahmed
  • Manish Motwani
  • Colin Cunnington
  • Chun Shing Kwok
  • Catherine Fullwood
  • Delvac Oceandy
  • Alan Fitchet
  • Grahame Kevin Goode
  • Matthew Luckie
  • Amir Masood Zaidi
  • Rajdeep Khattar
  • Mamas Andreas Mamas

Abstract

Background: Predicting which individuals will have a decline in left ventricular (LV) function after pacemaker implantation remains an important challenge. We investigated whether LV global longitudinal strain (GLS), measured by 2D speckle tracking strain echocardiography, can identify patients at risk of pacing-induced left ventricular dysfunction (PIVD) or pacing-induced cardiomyopathy (PICMP). Methods: Fifty-five patients with atrioventricular block and preserved LV function underwent dual-chamber pacemaker implantation and were followed with serial transthoracic echocardiography for 12 months for the development of PIVD (defined as a reduction in LV ejection fraction (LVEF) ≥5 percentage points at 12 months) or PICMP (reduction in LVEF to

Suggested Citation

  • Fozia Zahir Ahmed & Manish Motwani & Colin Cunnington & Chun Shing Kwok & Catherine Fullwood & Delvac Oceandy & Alan Fitchet & Grahame Kevin Goode & Matthew Luckie & Amir Masood Zaidi & Rajdeep Khatta, 2017. "One-Month Global Longitudinal Strain Identifies Patients Who Will Develop Pacing-Induced Left Ventricular Dysfunction over Time: The Pacing and Ventricular Dysfunction (PAVD) Study," PLOS ONE, Public Library of Science, vol. 12(1), pages 1-14, January.
  • Handle: RePEc:plo:pone00:0162072
    DOI: 10.1371/journal.pone.0162072
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