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Rheumatoid Arthritis Disease Activity Is Determinant for ABCB1 and ABCG2 Drug-Efflux Transporters Function

Author

Listed:
  • Yemil Atisha-Fregoso
  • Guadalupe Lima
  • Virginia Pascual-Ramos
  • Miguel Baños-Peláez
  • Hilda Fragoso-Loyo
  • Juan Jakez-Ocampo
  • Irazú Contreras-Yáñez
  • Luis Llorente

Abstract

Objective: To compare drug efflux function of ABCB1 and ABCG2 transporters in rheumatoid arthritis (RA) patients with active disease and in remission. Methods: Twenty two active RA patients (DAS28 ≥3.2) and 22 patients in remission (DAS28

Suggested Citation

  • Yemil Atisha-Fregoso & Guadalupe Lima & Virginia Pascual-Ramos & Miguel Baños-Peláez & Hilda Fragoso-Loyo & Juan Jakez-Ocampo & Irazú Contreras-Yáñez & Luis Llorente, 2016. "Rheumatoid Arthritis Disease Activity Is Determinant for ABCB1 and ABCG2 Drug-Efflux Transporters Function," PLOS ONE, Public Library of Science, vol. 11(7), pages 1-11, July.
    • Handle: RePEc:plo:pone00:0159556
    DOI: 10.1371/journal.pone.0159556
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