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Age-Dependent Morphologic Alterations in the Outer Retinal and Choroidal Thicknesses Using Swept Source Optical Coherence Tomography

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  • Ichiro Maruko
  • Hisaya Arakawa
  • Hideki Koizumi
  • Reiko Izumi
  • Hiromi Sunagawa
  • Tomohiro Iida

Abstract

Purpose: To evaluate the age-dependent morphologic alterations in the outer retina and choroid at the macula using swept-source optical coherence tomography (OCT). Methods: Thirty eyes (30 normal subjects; average age, 49 years) were examined; five (age range, third-eighth decades of life) had refractive errors of ±2 diopters or less and no fundus abnormalities. An Early Treatment Diabetic Retinopathy Study (ETDRS) map of the outer retinal and choroidal thickness was constructed using swept-source OCT. The outer retinal and choroidal segmentation lines were drawn automatically, partially manually, within 6 millimeters of the macula. Results: The mean outer retinal and choroidal thicknesses in the 6-millimeter-diameter circle were 145±13 and 236±68 microns, respectively. The choroidal thickness and age were negatively (r = -0.66, P

Suggested Citation

  • Ichiro Maruko & Hisaya Arakawa & Hideki Koizumi & Reiko Izumi & Hiromi Sunagawa & Tomohiro Iida, 2016. "Age-Dependent Morphologic Alterations in the Outer Retinal and Choroidal Thicknesses Using Swept Source Optical Coherence Tomography," PLOS ONE, Public Library of Science, vol. 11(7), pages 1-8, July.
    • Handle: RePEc:plo:pone00:0159439
    DOI: 10.1371/journal.pone.0159439
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