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Diagnostic Accuracy of 2D-Shear Wave Elastography for Liver Fibrosis Severity: A Meta-Analysis

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  • Tian’an Jiang
  • Guo Tian
  • Qiyu Zhao
  • Dexing Kong
  • Chao Cheng
  • Liyun Zhong
  • Lanjuan Li

Abstract

Purpose: To evaluate the accuracy of shear wave elastography (SWE) in the quantitative diagnosis of liver fibrosis severity. Methods: The published literatures were systematically retrieved from PubMed, Embase, Web of science and Scopus up to May 13th, 2016. Included studies reported the pooled sensitivity, specificity, positive and negative predictive values, as well as the diagnostic odds ratio of SWE in populations with liver fibrosis. A bivariate mixed-effects regression model was used, which was estimated by the I2 statistics. The quality of articles was evaluated by quality assessment of diagnostic accuracy studies (QUADAS). Results: Thirteen articles including 2303 patients were qualified for the study. The pooled sensitivity and specificity of SWE for the diagnosis of liver fibrosis are as follows: ≥F1 0.76 (p

Suggested Citation

  • Tian’an Jiang & Guo Tian & Qiyu Zhao & Dexing Kong & Chao Cheng & Liyun Zhong & Lanjuan Li, 2016. "Diagnostic Accuracy of 2D-Shear Wave Elastography for Liver Fibrosis Severity: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(6), pages 1-13, June.
    • Handle: RePEc:plo:pone00:0157219
    DOI: 10.1371/journal.pone.0157219
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