IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0141123.html
   My bibliography  Save this article

Radical Prostatectomy versus External Beam Radiotherapy for cT1-4N0M0 Prostate Cancer: Comparison of Patient Outcomes Including Mortality

Author

Listed:
  • Satoru Taguchi
  • Hiroshi Fukuhara
  • Kenshiro Shiraishi
  • Keiichi Nakagawa
  • Teppei Morikawa
  • Shigenori Kakutani
  • Yuta Takeshima
  • Hideyo Miyazaki
  • Tetsuya Fujimura
  • Tohru Nakagawa
  • Haruki Kume
  • Yukio Homma

Abstract

Background: Although radical prostatectomy (RP) and external beam radiotherapy (EBRT) have been considered as comparable treatments for localized prostate cancer (PC), it is controversial which treatment is better. The present study aimed to compare outcomes, including mortality, of RP and EBRT for localized PC. Methods: We retrospectively analyzed 891 patients with cT1-4N0M0 PC who underwent either RP (n = 569) or EBRT (n = 322) with curative intent at our single institution between 2005 and 2012. Of the EBRT patients, 302 (93.8%) underwent intensity-modulated radiotherapy. Primary endpoints were overall survival (OS) and cancer-specific survival (CSS). Related to these, other-cause mortality (OCM) was also calculated. Biochemical recurrence-free survival was assessed as a secondary endpoint. Cox proportional hazards model was used for multivariate analysis. Results: Median follow-up durations were 53 and 45 months, and median ages were 66 and 70 years (P

Suggested Citation

  • Satoru Taguchi & Hiroshi Fukuhara & Kenshiro Shiraishi & Keiichi Nakagawa & Teppei Morikawa & Shigenori Kakutani & Yuta Takeshima & Hideyo Miyazaki & Tetsuya Fujimura & Tohru Nakagawa & Haruki Kume & , 2015. "Radical Prostatectomy versus External Beam Radiotherapy for cT1-4N0M0 Prostate Cancer: Comparison of Patient Outcomes Including Mortality," PLOS ONE, Public Library of Science, vol. 10(10), pages 1-12, October.
    • Handle: RePEc:plo:pone00:0141123
    DOI: 10.1371/journal.pone.0141123
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0141123
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0141123&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0141123?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0141123. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.