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Predictors of Persistent Anaemia in the First Year of Antiretroviral Therapy: A Retrospective Cohort Study from Goma, the Democratic Republic of Congo

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  • Pierre Zalagile Akilimali
  • Espérance Kashala-Abotnes
  • Patou Masika Musumari
  • Patrick Kalambayi Kayembe
  • Thorkild Tylleskar
  • Mala Ali Mapatano

Abstract

Background: Anaemia is associated with adverse outcomes including early death in the first year of antiretroviral therapy (ART). This study reports on the factors associated with persistent anaemia among HIV-infected patients initiating ART in the Democratic Republic of Congo (DR Congo). Methods: We conducted a retrospective cohort study and analyzed data from patients receiving HIV care between January 2004 and December 2012 at two major hospitals in Goma, DR Congo. Haemoglobin concentrations of all patients on ART regimen were obtained prior to and within one year of ART initiation. A logistic regression model was used to identify the predictors of persistent anaemia after 12 months of ART. Results: Of 756 patients, 69% of patients were anaemic (IC95%: 65.7–72.3) at baseline. After 12 months of follow up, there was a 1.2 g/dl average increase of haemoglobin concentration (P

Suggested Citation

  • Pierre Zalagile Akilimali & Espérance Kashala-Abotnes & Patou Masika Musumari & Patrick Kalambayi Kayembe & Thorkild Tylleskar & Mala Ali Mapatano, 2015. "Predictors of Persistent Anaemia in the First Year of Antiretroviral Therapy: A Retrospective Cohort Study from Goma, the Democratic Republic of Congo," PLOS ONE, Public Library of Science, vol. 10(10), pages 1-11, October.
    • Handle: RePEc:plo:pone00:0140240
    DOI: 10.1371/journal.pone.0140240
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