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Body Mass Index and Mortality in the General Population and in Subjects with Chronic Disease in Korea: A Nationwide Cohort Study (2002-2010)

Author

Listed:
  • Nam Hoon Kim
  • Juneyoung Lee
  • Tae Joon Kim
  • Nan Hee Kim
  • Kyung Mook Choi
  • Sei Hyun Baik
  • Dong Seop Choi
  • Rodica Pop-Busui
  • Yousung Park
  • Sin Gon Kim

Abstract

Background: The association between body mass index (BMI) and mortality is not conclusive, especially in East Asian populations. Furthermore, the association has been neither supported by recent data, nor assessed after controlling for weight changes. Methods: We evaluated the relationship between BMI and all-cause or cause-specific mortality, using prospective cohort data by the National Health Insurance Service in Korea, which consisted of more than one million subjects. A total of 153,484 Korean adults over 30 years of age without pre-existing cardiovascular disease or cancer at baseline were followed-up until 2010 (mean follow-up period = 7.91 ± 0.59 years). Study subjects repeatedly measured body weight 3.99 times, on average. Results: During follow-up, 3,937 total deaths occurred; 557 deaths from cardiovascular disease, and 1,224 from cancer. In multiple-adjusted analyses, U-shaped associations were found between BMI and mortality from any cause, cardiovascular disease, and cancer after adjustment for age, sex, smoking status, alcohol consumption, physical activity, socioeconomic status, and weight change. Subjects with a BMI

Suggested Citation

  • Nam Hoon Kim & Juneyoung Lee & Tae Joon Kim & Nan Hee Kim & Kyung Mook Choi & Sei Hyun Baik & Dong Seop Choi & Rodica Pop-Busui & Yousung Park & Sin Gon Kim, 2015. "Body Mass Index and Mortality in the General Population and in Subjects with Chronic Disease in Korea: A Nationwide Cohort Study (2002-2010)," PLOS ONE, Public Library of Science, vol. 10(10), pages 1-16, October.
    • Handle: RePEc:plo:pone00:0139924
    DOI: 10.1371/journal.pone.0139924
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