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Smoking, Suicidality and Psychosis: A Systematic Meta-Analysis

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  • Anoop Sankaranarayanan
  • Serafino Mancuso
  • Helen Wilding
  • Suhaila Ghuloum
  • David Castle

Abstract

The aim of this study is to systematically review the literature that explored the association between smoking and suicidal risk among those with serious mental illness and to estimate the risk of suicidal behaviors attributable to smoking among this patient group. Multiple databases (CINAHL, PsycINFO, EMBASE, Informit Health Collection and the Cochrane Library databases) were searched from 1 January 1975 through 15 January 2014, along with references from relevant articles for observational studies that ascertained the association between smoking and suicidal behaviors among patients with psychotic disorders conducted in adult patients. Thirteen studies involving 6813 patients with severe mental illness were included. We found that smoking was significantly associated with suicidality in psychosis with an Odds Ratio of 2.12 (95% CI 1.67–2.7). Smoking is associated with suicidal risk amongst individuals with a severe mental illness; however, it is still unclear whether this represents a true risk factor or a confounder or a mediator via mechanisms, hitherto unknown, needs to be studied further.

Suggested Citation

  • Anoop Sankaranarayanan & Serafino Mancuso & Helen Wilding & Suhaila Ghuloum & David Castle, 2015. "Smoking, Suicidality and Psychosis: A Systematic Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(9), pages 1-14, September.
  • Handle: RePEc:plo:pone00:0138147
    DOI: 10.1371/journal.pone.0138147
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    Cited by:

    1. María Teresa Carrasco-Barrios & Paloma Huertas & Paloma Martín & Carlos Martín & Mª Carmen Castillejos & Eleni Petkari & Berta Moreno-Küstner, 2020. "Determinants of Suicidality in the European General Population: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 17(11), pages 1-24, June.

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