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New Cerebral Lesions at Magnetic Resonance Imaging after Carotid Artery Stenting Versus Endarterectomy: An Updated Meta-Analysis

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  • Giuseppe Gargiulo
  • Anna Sannino
  • Eugenio Stabile
  • Cinzia Perrino
  • Bruno Trimarco
  • Giovanni Esposito

Abstract

Background: Carotid endarterectomy (CEA) or stenting (CAS) are associated with a relatively low rate of clinical events, but diffusion-weighted imaging (DWI) is increasingly being used to compare the incidence of new ischemic lesions. Therefore, we conducted an updated meta-analysis on the occurrence of post-procedural new DWI lesions after CAS versus CEA. Methods and Results: MEDLINE, Cochrane, ISI Web of Science and SCOPUS databases were searched and 20 studies (2 randomized and 18 non-randomized) with a total of 2104 procedures (CAS = 989; CEA = 1115) were included. The incidence of new DWI cerebral lesions was significantly greater after CAS than CEA (40.3% vs 12.2%; 20 studies; 2104 patients; odds ratio [OR] 5.17; 95% confidence interval [CI], 3.31-8.06; p

Suggested Citation

  • Giuseppe Gargiulo & Anna Sannino & Eugenio Stabile & Cinzia Perrino & Bruno Trimarco & Giovanni Esposito, 2015. "New Cerebral Lesions at Magnetic Resonance Imaging after Carotid Artery Stenting Versus Endarterectomy: An Updated Meta-Analysis," PLOS ONE, Public Library of Science, vol. 10(5), pages 1-11, May.
    • Handle: RePEc:plo:pone00:0129209
    DOI: 10.1371/journal.pone.0129209
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