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Clinical Outcomes of FP-7/8 Ahmed Glaucoma Valves in the Management of Refractory Glaucoma in the Mainland Chinese Population

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  • Yingting Zhu
  • Yantao Wei
  • Xuejiao Yang
  • Shuifeng Deng
  • Zuohong Li
  • Fei Li
  • Yehong Zhuo

Abstract

Background: To evaluate the efficacy and safety of the Ahmed glaucoma valve (AGV) and the risk factors associated with AGV implantation failure in a population of Chinese patients with refractory glaucoma. Method: In total, 79 eyes with refractory glaucoma from 79 patients treated in our institution from November 2007 to November 2010 were enrolled in this retrospective study. The demographic data, preoperative and postoperative intraocular pressures (IOPs), best corrected visual acuity (BCVA), number of anti-glaucoma medications used, completed and qualified surgery success rates and postoperative complications were recorded to evaluate the outcomes of AGV implantation. Factors that were associated with implant failure were determined using Cox proportional hazard regression model analysis and multiple linear regression analysis. Principle Findings: The average follow-up time was 12.7±5.8 months (mean±SD). We observed a significant reduction in the mean IOP from 39.9±12.6 mm Hg before surgery to 19.3±9.6 mm Hg at the final follow-up. The complete success rate was 59.5%, and the qualified success rate was 83.5%. The number of previous surgeries was negatively correlated with qualified success rate (P

Suggested Citation

  • Yingting Zhu & Yantao Wei & Xuejiao Yang & Shuifeng Deng & Zuohong Li & Fei Li & Yehong Zhuo, 2015. "Clinical Outcomes of FP-7/8 Ahmed Glaucoma Valves in the Management of Refractory Glaucoma in the Mainland Chinese Population," PLOS ONE, Public Library of Science, vol. 10(5), pages 1-13, May.
    • Handle: RePEc:plo:pone00:0127658
    DOI: 10.1371/journal.pone.0127658
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