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Comparison of the Association of Sac Growth and Coil Compaction with Recurrence in Coil Embolized Cerebral Aneurysms

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  • Anna L Hoppe
  • Madhavan L Raghavan
  • David M Hasan

Abstract

Background and Purpose: In recurrent cerebral aneurysms treated by coil embolization, coil compaction is regarded as the presumptive mechanism. We test the hypothesis that aneurysm growth is the primary recurrence mechanism. We also test the hypothesis that the coil mass will translate a measurable extent when recurrence occurs. Methods: An objective, quantitative image analysis protocol was developed to determine the volumes of aneurysms and coil masses during initial and follow-up visits from 3D rotational angiograms. The population consisted of 15 recurrence and 12 non-recurrence control aneurysms initially completely coiled at a single center. An investigator sensitivity study was performed to assess the objectivity of the methods. Paired Wilcoxon tests (p

Suggested Citation

  • Anna L Hoppe & Madhavan L Raghavan & David M Hasan, 2015. "Comparison of the Association of Sac Growth and Coil Compaction with Recurrence in Coil Embolized Cerebral Aneurysms," PLOS ONE, Public Library of Science, vol. 10(4), pages 1-12, April.
    • Handle: RePEc:plo:pone00:0123017
    DOI: 10.1371/journal.pone.0123017
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