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Keratometric Index Obtained by Fourier-Domain Optical Coherence Tomography

Author

Listed:
  • Yanjun Hua
  • Aleksander Stojanovic
  • Tor Paaske Utheim
  • Xiangjun Chen
  • Sten Ræder
  • Jinhai Huang
  • Qinmei Wang

Abstract

Purpose: To determine the keratometric indices calculated based on parameters obtained by Fourier-domain optical coherence tomography (FD-OCT). Methods: The ratio of anterior corneal curvature to posterior corneal curvature (Ratio) and keratometric index (N) were calculated within central 3 mm zone with the RTVue FD-OCT (RTVue, Optovue, Inc.) in 186 untreated eyes, 60 post-LASIK/PRK eyes, and 39 keratoconus eyes. The total corneal powers were calculated using different keratometric indices: Kcal based on the mean calculated keratometric index, K1.3315 calculated by the keratometric index of 1.3315, and K1.3375 calculated by the keratometric index of 1.3375. In addition, the total corneal powers based on Gaussian optics formula (Kactual) were calculated. Results: The means for Ratio in untreated controls, post-LASIK/PRK group and keratoconus group were 1.176 ± 0.022 (95% confidence interval (CI), 1.172–1.179), 1.314 ± 0.042 (95%CI, 1.303–1.325) and 1.229 ± 0.118 (95%CI, 1.191–1.267), respectively. And the mean calculated keratometric index in untreated controls, post-LASIK/PRK group and keratoconus group were 1.3299 ± 0.00085 (95%CI, 1.3272–1.3308), 1.3242 ± 0.00171 (95%CI, 1.3238–1.3246) and 1.3277 ± 0.0046 (95%CI, 1.3263–1.3292), respectively. All the parameters were normally distributed. The differences between Kcal and Kactual, K1.3315 and Kactual, and K1.3375 and Kactual were 0.00 ± 0.11 D, 0.21 ± 0.11 D and 0.99 ± 0.12 D, respectively, in untreated controls; -0.01 ± 0.20 D, 0.85 ± 0.18 D and 1.56 ± 0.16 D, respectively, in post-LASIK/PRK group; and 0.03 ± 0.67 D, 0.56 ± 0.70 D and 1.40 ± 0.76 D, respectively, in keratoconus group. Conclusion: The calculated keratometric index is negatively related to the ratio of anterior corneal curvature to posterior corneal curvature in untreated, post-LASIK/PRK, and keratoconus eyes, respectively. Using the calculated keratometric index may improve the prediction accuracies of total corneal powers in untreated controls, but not in post-LASIK/PRK and keratoconus eyes.

Suggested Citation

  • Yanjun Hua & Aleksander Stojanovic & Tor Paaske Utheim & Xiangjun Chen & Sten Ræder & Jinhai Huang & Qinmei Wang, 2015. "Keratometric Index Obtained by Fourier-Domain Optical Coherence Tomography," PLOS ONE, Public Library of Science, vol. 10(4), pages 1-12, April.
    • Handle: RePEc:plo:pone00:0122441
    DOI: 10.1371/journal.pone.0122441
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    Cited by:

    1. Yanjun Hua & Wei Qiu & Qiuyi Xiao & Qiang Wu, 2018. "Precision (repeatability and reproducibility) of ocular parameters obtained by the Tomey OA-2000 biometer compared to the IOLMaster in healthy eyes," PLOS ONE, Public Library of Science, vol. 13(2), pages 1-11, February.

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