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Impaired Glucose Metabolism among Those with and without Diagnosed Diabetes and Mortality: A Cohort Study Using Health Survey for England Data

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Listed:
  • Vanessa L Z Gordon-Dseagu
  • Jennifer S Mindell
  • Andrew Steptoe
  • Alison Moody
  • Jane Wardle
  • Panayotes Demakakos
  • Nicola J Shelton

Abstract

Background: The extent that controlled diabetes impacts upon mortality, compared with uncontrolled diabetes, and how pre-diabetes alters mortality risk remain issues requiring clarification. Methods: We carried out a cohort study of 22,106 Health Survey for England participants with a HbA1C measurement linked with UK mortality records. We estimated hazard ratios (HRs) of all-cause, cancer and cardiovascular disease (CVD) mortality and 95% confidence intervals (CI) using Cox regression. Results: Average follow-up time was seven years and there were 1,509 deaths within the sample. Compared with the non-diabetic and normoglycaemic group (HbA1C

Suggested Citation

  • Vanessa L Z Gordon-Dseagu & Jennifer S Mindell & Andrew Steptoe & Alison Moody & Jane Wardle & Panayotes Demakakos & Nicola J Shelton, 2015. "Impaired Glucose Metabolism among Those with and without Diagnosed Diabetes and Mortality: A Cohort Study Using Health Survey for England Data," PLOS ONE, Public Library of Science, vol. 10(3), pages 1-13, March.
  • Handle: RePEc:plo:pone00:0119882
    DOI: 10.1371/journal.pone.0119882
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