IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0115755.html
   My bibliography  Save this article

Statin Use and Cognitive Function: Population-Based Observational Study with Long-Term Follow-Up

Author

Listed:
  • Hanneke Joosten
  • Sipke T Visser
  • Marlise E van Eersel
  • Ron T Gansevoort
  • Henk J G Bilo
  • Joris P Slaets
  • Gerbrand J Izaks

Abstract

We aimed to evaluate the association between statin use and cognitive function. Cognitive function was measured with the Ruff Figural Fluency Test (RFFT; worst score, 0; best score, 175 points) and the Visual Association Test (VAT; low performance, 0–10; high performance, 11–12 points) in an observational study that included 4,095 community-dwelling participants aged 35–82 years. Data on statin use were obtained from a computerized pharmacy database. Analysis were done for the total cohort and subsamples matched on cardiovascular risk (N = 1232) or propensity score for statin use (N = 3609). We found that a total of 904 participants (10%) used a statin. Statin users were older than non-users: mean age (SD) 61 (10) vs. 52 (11) years (p

Suggested Citation

  • Hanneke Joosten & Sipke T Visser & Marlise E van Eersel & Ron T Gansevoort & Henk J G Bilo & Joris P Slaets & Gerbrand J Izaks, 2014. "Statin Use and Cognitive Function: Population-Based Observational Study with Long-Term Follow-Up," PLOS ONE, Public Library of Science, vol. 9(12), pages 1-15, December.
    • Handle: RePEc:plo:pone00:0115755
    DOI: 10.1371/journal.pone.0115755
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115755
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0115755&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0115755?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0115755. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.