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Evaluation of Intereye Corneal Asymmetry in Patients with Keratoconus. A Scheimpflug Imaging Study

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  • Lóránt Dienes
  • Kinga Kránitz
  • Éva Juhász
  • Andrea Gyenes
  • Ágnes Takács
  • Kata Miháltz
  • Zoltán Z Nagy
  • Illés Kovács

Abstract

Purpose: To assess the correlation between keratoconus severity and intereye asymmetry of pachymetric data and posterior elevation values and to evaluate their combined accuracy in discriminating normal corneas from those with keratoconus. Methods: This study included 97 patients: 65 subjects with bilateral normal corneas (NC) and 32 with keratoconus (KC). Central corneal thickness (CCT), thinnest corneal thickness (ThCT) and posterior elevation (PE) at the thinnest point of the cornea were measured in both eyes using Scheimpflug imaging. Intereye asymmetry and its correlation with keratoconus severity were calculated for each variable. The area under the receiver operating characteristic curve (AUROC) was used to compare predictive accuracy of different variables for keratoconus. Results: In normal eyes, intereye differences were significantly lower compared with the keratoconus eyes (p

Suggested Citation

  • Lóránt Dienes & Kinga Kránitz & Éva Juhász & Andrea Gyenes & Ágnes Takács & Kata Miháltz & Zoltán Z Nagy & Illés Kovács, 2014. "Evaluation of Intereye Corneal Asymmetry in Patients with Keratoconus. A Scheimpflug Imaging Study," PLOS ONE, Public Library of Science, vol. 9(10), pages 1-6, October.
    • Handle: RePEc:plo:pone00:0108882
    DOI: 10.1371/journal.pone.0108882
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    Cited by:

    1. Ye Li & Akilesh Gokul & Charles McGhee & Mohammed Ziaei, 2021. "Repeatability of corneal and epithelial thickness measurements with anterior segment optical coherence tomography in keratoconus," PLOS ONE, Public Library of Science, vol. 16(6), pages 1-10, June.

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