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A 346 Case Analysis for Laparoscopic Spleen-Preserving No.10 Lymph Node Dissection for Proximal Gastric Cancer: A Single Center Study

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  • Chang-Ming Huang
  • Jun-Rong Zhang
  • Chao-Hui Zheng
  • Ping Li
  • Jian-Wei Xie
  • Jia-Bin Wang
  • Jian-Xian Lin
  • Jun Lu
  • Qi-Yue Chen

Abstract

Purpose: This study was designed to formulate a model that efficiently predicts splenic hilar lymph node metastasis (SHLNM) in patients with proximal gastric cancer and to assess indications for laparoscopic spleen-preserving no.10 lymph node dissection (LSPNo.10LND) based on this model. Methods: Patients (N = 346) with proximal gastric cancer who underwent LSPNo.10LND from January 2010 to October 2013 were prospectively enrolled and retrospectively evaluated. Groups of patients with and without SHLNM were compared, and independent risk factors for SHLNM determined. An optimal predictive model of SHLNM in patients with proximal gastric cancer was well established. Results: Of the 346 patients with proximal gastric cancer, only 35 (10.1%) were diagnosed with SHLNM. Depth of invasion, tumor location and metastases to No.7 and No.11 lymph nodes (LNs) were independent risk factors for SHLNM (p

Suggested Citation

  • Chang-Ming Huang & Jun-Rong Zhang & Chao-Hui Zheng & Ping Li & Jian-Wei Xie & Jia-Bin Wang & Jian-Xian Lin & Jun Lu & Qi-Yue Chen, 2014. "A 346 Case Analysis for Laparoscopic Spleen-Preserving No.10 Lymph Node Dissection for Proximal Gastric Cancer: A Single Center Study," PLOS ONE, Public Library of Science, vol. 9(9), pages 1-7, September.
    • Handle: RePEc:plo:pone00:0108480
    DOI: 10.1371/journal.pone.0108480
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