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Inter-Vendor Reproducibility of Pseudo-Continuous Arterial Spin Labeling at 3 Tesla

Author

Listed:
  • Henri J M M Mutsaerts
  • Rebecca M E Steketee
  • Dennis F R Heijtel
  • Joost P A Kuijer
  • Matthias J P van Osch
  • Charles B L M Majoie
  • Marion Smits
  • Aart J Nederveen

Abstract

Purpose: Prior to the implementation of arterial spin labeling (ASL) in clinical multi-center studies, it is important to establish its status quo inter-vendor reproducibility. This study evaluates and compares the intra- and inter-vendor reproducibility of pseudo-continuous ASL (pCASL) as clinically implemented by GE and Philips. Material and Methods: 22 healthy volunteers were scanned twice on both a 3T GE and a 3T Philips scanner. The main difference in implementation between the vendors was the readout module: spiral 3D fast spin echo vs. 2D gradient-echo echo-planar imaging respectively. Mean and variation of cerebral blood flow (CBF) were compared for the total gray matter (GM) and white matter (WM), and on a voxel-level. Results: Whereas the mean GM CBF of both vendors was almost equal (p = 1.0), the mean WM CBF was significantly different (p

Suggested Citation

  • Henri J M M Mutsaerts & Rebecca M E Steketee & Dennis F R Heijtel & Joost P A Kuijer & Matthias J P van Osch & Charles B L M Majoie & Marion Smits & Aart J Nederveen, 2014. "Inter-Vendor Reproducibility of Pseudo-Continuous Arterial Spin Labeling at 3 Tesla," PLOS ONE, Public Library of Science, vol. 9(8), pages 1-10, August.
    • Handle: RePEc:plo:pone00:0104108
    DOI: 10.1371/journal.pone.0104108
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