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Culprit Vessel Only versus Multivessel Percutaneous Coronary Intervention in Patients Presenting with ST-Segment Elevation Myocardial Infarction and Multivessel Disease

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  • Dongfeng Zhang
  • Xiantao Song
  • Shuzheng Lv
  • Fei Yuan
  • Feng Xu
  • Min Zhang
  • Wei Li
  • Shuai Yan

Abstract

Background: The best strategy for ST-segment elevation myocardial infarction (STEMI) patients with multivessel disease (MVD), who underwent primary percutaneous coronary intervention (PCI) in the acute phase, is not well established. Objectives: Our goal was to conduct a meta-analysis comparing culprit vessel only percutaneous coronary intervention (culprit PCI) with multivessel percutaneous coronary intervention (MV-PCI) for treatment of patients with STEMI and MVD. Methods: Pubmed, Elsevier, Embase, and China National Knowledge Infrastructure (CNKI) databases were systematically searched for randomized and nonrandomized studies comparing culprit PCI and MV-PCI strategies during the index procedure. A meta-analysis was performed using Review Manager 5.1 (Cochrane Center, Denmark). Results: Four randomized and fourteen nonrandomized studies involving 39,390 patients were included. MV-PCI strategy is associated with an increased short-term mortality (OR: 0.50, 95% CI: 0.32 to 0.77, p = 0.002), long-term mortality (OR: 0.52, 95% CI: 0.36 to 0.74, p

Suggested Citation

  • Dongfeng Zhang & Xiantao Song & Shuzheng Lv & Fei Yuan & Feng Xu & Min Zhang & Wei Li & Shuai Yan, 2014. "Culprit Vessel Only versus Multivessel Percutaneous Coronary Intervention in Patients Presenting with ST-Segment Elevation Myocardial Infarction and Multivessel Disease," PLOS ONE, Public Library of Science, vol. 9(3), pages 1-11, March.
    • Handle: RePEc:plo:pone00:0092316
    DOI: 10.1371/journal.pone.0092316
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