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Fever Burden Is an Independent Predictor for Prognosis of Traumatic Brain Injury

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  • Long Bao
  • Du Chen
  • Li Ding
  • Weihua Ling
  • Feng Xu

Abstract

Objective: To evaluate fever burden as an independent predictor for prognosis of traumatic brain injury (TBI). Methods: This retrospective study involved 355 TBI patients with Glasgow Coma Scale (GCS) ≤14, who presented at the emergency department of our hospital between November 2010 and October 2012. At 6 months follow-up, patients were divided into 5 groups based on Glasgow Outcome Scale (GOS) and dichotomized to GOS score (high (4 to 5) vs. low (1 to 3)). The relationship between fever burden and GOS was assessed. Results: Fever burden increased as GOS scores decreased from 5 to 2, except for score 1 of GOS, which corresponded to a significant lower fever burden. Following dichotomization, patients in the high GOS group were younger, and showed less abnormal pupil reactivity (P

Suggested Citation

  • Long Bao & Du Chen & Li Ding & Weihua Ling & Feng Xu, 2014. "Fever Burden Is an Independent Predictor for Prognosis of Traumatic Brain Injury," PLOS ONE, Public Library of Science, vol. 9(3), pages 1-5, March.
    • Handle: RePEc:plo:pone00:0090956
    DOI: 10.1371/journal.pone.0090956
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