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Sleep-Wake Cycle in Young and Older Persons with a Lifetime History of Mood Disorders

Author

Listed:
  • Rébecca Robillard
  • Sharon L Naismith
  • Kristie Leigh Smith
  • Naomi L Rogers
  • Django White
  • Zoe Terpening
  • Tony K C Ip
  • Daniel F Hermens
  • Bradley Whitwell
  • Elizabeth M Scott
  • Ian B Hickie

Abstract

Considering the marked changes in sleep and circadian rhythms across the lifespan, age may contribute to the heterogeneity in sleep-wake profiles linked to mood disorders. This study aimed to investigate the contributions of age and depression severity to sleep-wake disturbances. The Hamilton Depression Rating Scale (HDRS) was administered to assess current symptoms severity in 238 persons with a history of a mood disorder between 12 and 90 years of age (y.o.). Actigraphy was recorded over five to 22 days. Regression analyses and analyses of variance [age (12–19 y.o., 20–39 y.o., 40–59 y.o., and ≥60 y.o.) by depression severity (HDRS

Suggested Citation

  • Rébecca Robillard & Sharon L Naismith & Kristie Leigh Smith & Naomi L Rogers & Django White & Zoe Terpening & Tony K C Ip & Daniel F Hermens & Bradley Whitwell & Elizabeth M Scott & Ian B Hickie, 2014. "Sleep-Wake Cycle in Young and Older Persons with a Lifetime History of Mood Disorders," PLOS ONE, Public Library of Science, vol. 9(2), pages 1-8, February.
    • Handle: RePEc:plo:pone00:0087763
    DOI: 10.1371/journal.pone.0087763
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