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Incidence of and Mortality from Type I Diabetes in Taiwan From 1999 through 2010: A Nationwide Cohort Study

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  • Wei-Hung Lin
  • Ming-Cheng Wang
  • Wei-Ming Wang
  • Deng-Chi Yang
  • Chen-Fuh Lam
  • Jun-Neng Roan
  • Chung-Yi Li

Abstract

Objective: To evaluate the secular trend in incidence of and mortality from Type 1 diabetes mellitus (T1DM) in Taiwan, 1999–2010. Methods: All 7,225 incident cases of T1DM were retrospectively retrieved from Taiwan's National Health Insurance Research Database from 1999 to 2010. Trend of bi-annual age- and sex-specific incidence rates of T1DM was calculated and tested with Poisson regression model. Standardized mortality ratios (SMRs) were calculated, using age-, sex-, and calendar years-specific mortality rates of the general population as the reference, to estimate the relative mortality risk of T1DM. Results: The number of male and female T1DM was 3,471 (48%) and 3,754 (52%), respectively. The annual number of incident T1DM increased from 543 in 1999 to 737 in 2010. The overall bi-annual incidence rate rose from 1999–00 to 2003–04 and mildly declined thereafter rose to 2009–10, with an insignificant trend (P = 0.489) over the study period. Regardless of gender, the higher age-specific incidence rate was noted in the younger groups (

Suggested Citation

  • Wei-Hung Lin & Ming-Cheng Wang & Wei-Ming Wang & Deng-Chi Yang & Chen-Fuh Lam & Jun-Neng Roan & Chung-Yi Li, 2014. "Incidence of and Mortality from Type I Diabetes in Taiwan From 1999 through 2010: A Nationwide Cohort Study," PLOS ONE, Public Library of Science, vol. 9(1), pages 1-7, January.
    • Handle: RePEc:plo:pone00:0086172
    DOI: 10.1371/journal.pone.0086172
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