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Detection of Progression of Glaucomatous Visual Field Damage Using the Point-Wise Method with the Binomial Test

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  • Ayako Karakawa
  • Hiroshi Murata
  • Hiroyo Hirasawa
  • Chihiro Mayama
  • Ryo Asaoka

Abstract

Purpose: To compare the performance of newly proposed point-wise linear regression (PLR) with the binomial test (binomial PLR) against mean deviation (MD) trend analysis and permutation analyses of PLR (PoPLR), in detecting global visual field (VF) progression in glaucoma. Methods: 15 VFs (Humphrey Field Analyzer, SITA standard, 24-2) were collected from 96 eyes of 59 open angle glaucoma patients (6.0 ± 1.5 [mean ± standard deviation] years). Using the total deviation of each point on the 2nd to 16th VFs (VF2-16), linear regression analysis was carried out. The numbers of VF test points with a significant trend at various probability levels (p

Suggested Citation

  • Ayako Karakawa & Hiroshi Murata & Hiroyo Hirasawa & Chihiro Mayama & Ryo Asaoka, 2013. "Detection of Progression of Glaucomatous Visual Field Damage Using the Point-Wise Method with the Binomial Test," PLOS ONE, Public Library of Science, vol. 8(10), pages 1-1, October.
    • Handle: RePEc:plo:pone00:0078630
    DOI: 10.1371/journal.pone.0078630
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