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Predictors of Beta-Blocker Intolerance and Mortality in Patients After Acute Coronary Syndrome

Author

Listed:
  • Laercio Martins De Stefano
  • Alex Lombardi Barbosa Ferraz
  • Ana Lúcia dos Anjos Ferreira
  • Ana Lúcia Gut
  • Ana Lúcia Cogni
  • Elaine Farah
  • Beatriz Bojikian Matsubara

Abstract

Purpose: To investigate the predictors of intolerance to beta-blockers treatment and the 6-month mortality in hospitalized patients with acute coronary syndrome (ACS). Methods: This was a single-center, prospective, and longitudinal study including 370 consecutive ACS patients in Killip class I or II. BBs were prescribed according to international guidelines and withdrawn if intolerance occurred. The study was approved by the institutional ethics committee of our university. Statistics: the clinical parameters evaluated at admission, and the related intolerance to BBs and death at 6 months were analyzed using logistic regression (p

Suggested Citation

  • Laercio Martins De Stefano & Alex Lombardi Barbosa Ferraz & Ana Lúcia dos Anjos Ferreira & Ana Lúcia Gut & Ana Lúcia Cogni & Elaine Farah & Beatriz Bojikian Matsubara, 2013. "Predictors of Beta-Blocker Intolerance and Mortality in Patients After Acute Coronary Syndrome," PLOS ONE, Public Library of Science, vol. 8(10), pages 1-1, October.
    • Handle: RePEc:plo:pone00:0077747
    DOI: 10.1371/journal.pone.0077747
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