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Awareness of and Willingness to Use Oral Pre-Exposure Prophylaxis for HIV Prevention among HIV-Serodiscordant Heterosexual Couples: A Cross-Sectional Survey in Xinjiang, China

Author

Listed:
  • Peierdun Mijiti
  • Dilixiati Yahepu
  • Xiaoni Zhong
  • Yong Sun
  • Ting Zhao
  • Zhen Zhao
  • Zaiyinuer Abuduaili
  • Hongfang Zhou
  • Fanliang Meng
  • Jianghong Dai
  • Ailong Huang

Abstract

Objectives: We aimed to investigate the awareness of and willingness to use oral pre-exposure prophylaxis (PrEP) for HIV prevention among HIV-negative partners in HIV-serodiscordant heterosexual couples in Xinjiang, China and determine factors that predict willingness to use oral PrEP. Methods: Between November 2009 and December 2010, a cross-sectional survey was carried out among 351 HIV-negative partners in HIV-serodiscordant heterosexual couples from three cities in Xinjiang, China. Participants completed a self-administered questionnaire to assess their awareness of and willingness to use oral PrEP. Additionally, blood samples were collected to test for HIV infection. Univariate and multivariate logistic regression analyses were performed to identify predictors of willingness to use oral PrEP. Results: Only 10 participants (2.8%) reported having heard of PrEP, and only two reported ever using PrEP. However, 297 (84.6%) reported that they were willing to use oral PrEP if it was proven to be both safe and effective. Results of multivariate analysis revealed the following independent predictors of willingness to use oral PrEP: monthly household income (adjusted odds ratio = 2.78,

Suggested Citation

  • Peierdun Mijiti & Dilixiati Yahepu & Xiaoni Zhong & Yong Sun & Ting Zhao & Zhen Zhao & Zaiyinuer Abuduaili & Hongfang Zhou & Fanliang Meng & Jianghong Dai & Ailong Huang, 2013. "Awareness of and Willingness to Use Oral Pre-Exposure Prophylaxis for HIV Prevention among HIV-Serodiscordant Heterosexual Couples: A Cross-Sectional Survey in Xinjiang, China," PLOS ONE, Public Library of Science, vol. 8(7), pages 1-8, July.
    • Handle: RePEc:plo:pone00:0067392
    DOI: 10.1371/journal.pone.0067392
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