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The Use of Biatain Ag in Hard-to-Heal Venous Leg Ulcers: Meta-Analysis of Randomised Controlled Trials

Author

Listed:
  • David Leaper
  • Christian Münter
  • Sylvie Meaume
  • Alessandro Scalise
  • Nacho Blanes Mompó
  • Birte Petersen Jakobsen
  • Finn Gottrup

Abstract

Background: Venous leg ulcers are common, troublesome, and their failure to heal is often related to a heavy bio-burden. Ionized silver has both anti-inflammatory and antimicrobial properties. The ulcer healing properties of the silver releasing foam dressing Biatain Ag has been examined in 4 randomized controlled trials (RCTs). Aim: To evaluate ulcer healing through a meta-analytic approach after treatment with either Biatain Ag or a non-active dressing. Patients and Methods: 685 subjects with pure or mixed hard-to-heal venous leg ulcers were included in the meta-analysis. Results: Biatain Ag showed a significant treatment effect (p

Suggested Citation

  • David Leaper & Christian Münter & Sylvie Meaume & Alessandro Scalise & Nacho Blanes Mompó & Birte Petersen Jakobsen & Finn Gottrup, 2013. "The Use of Biatain Ag in Hard-to-Heal Venous Leg Ulcers: Meta-Analysis of Randomised Controlled Trials," PLOS ONE, Public Library of Science, vol. 8(7), pages 1-7, July.
    • Handle: RePEc:plo:pone00:0067083
    DOI: 10.1371/journal.pone.0067083
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    Cited by:

    1. Gregor B E Jemec & Jean Charles Kerihuel & Karen Ousey & Sanne Lise Lauemøller & David John Leaper, 2014. "Cost-Effective Use of Silver Dressings for the Treatment of Hard-to-Heal Chronic Venous Leg Ulcers," PLOS ONE, Public Library of Science, vol. 9(6), pages 1-6, June.

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