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Volumetric Electromagnetic Phase-Shift Spectroscopy of Brain Edema and Hematoma

Author

Listed:
  • Cesar A Gonzalez
  • Jose A Valencia
  • Alfredo Mora
  • Fernando Gonzalez
  • Beatriz Velasco
  • Martin A Porras
  • Javier Salgado
  • Salvador M Polo
  • Nidiyare Hevia-Montiel
  • Sergio Cordero
  • Boris Rubinsky

Abstract

Motivated by the need of poor and rural Mexico, where the population has limited access to advanced medical technology and services, we have developed a new paradigm for medical diagnostic based on the technology of “Volumetric Electromagnetic Phase Shift Spectroscopy” (VEPS), as an inexpensive partial substitute to medical imaging. VEPS, can detect changes in tissue properties inside the body through non-contact, multi-frequency electromagnetic measurements from the exterior of the body, and thereby provide rapid and inexpensive diagnostics in a way that is amenable for use in economically disadvantaged parts of the world. We describe the technology and report results from a limited pilot study with 46 healthy volunteers and eight patients with CT radiology confirmed brain edema and brain hematoma. Data analysis with a non-parametric statistical Mann-Whitney U test, shows that in the frequency range of from 26 MHz to 39 MHz, VEPS can distinguish non-invasively and without contact, with a statistical significance of p

Suggested Citation

  • Cesar A Gonzalez & Jose A Valencia & Alfredo Mora & Fernando Gonzalez & Beatriz Velasco & Martin A Porras & Javier Salgado & Salvador M Polo & Nidiyare Hevia-Montiel & Sergio Cordero & Boris Rubinsky, 2013. "Volumetric Electromagnetic Phase-Shift Spectroscopy of Brain Edema and Hematoma," PLOS ONE, Public Library of Science, vol. 8(5), pages 1-10, May.
    • Handle: RePEc:plo:pone00:0063223
    DOI: 10.1371/journal.pone.0063223
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