IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0060443.html
   My bibliography  Save this article

Smoking and Risk of Erectile Dysfunction: Systematic Review of Observational Studies with Meta-Analysis

Author

Listed:
  • Shiyi Cao
  • Xiaoxu Yin
  • Yunxia Wang
  • Hongfeng Zhou
  • Fujian Song
  • Zuxun Lu

Abstract

Background: There are many recent observational studies on smoking and risk of erectile dysfunction (ED) and whether smoking increases the risk of ED is still inconclusive. The objective of this meta-analysis was to synthesize evidence from studies that evaluated the association between smoking and the risk of ED. Methods: We searched PubMed, Embase, Web of Science, and Scopus in January 2013 to identify cohort and case-control studies that evaluated the association between smoking and ED. Study quality of included studies was assessed by the Newcastle-Ottawa scale. Random-effects meta-analyses were used to combine the results of included studies. Results: Four prospective cohort studies and four case-control studies involving 28, 586 participants were included. Because of significant heterogeneity after including case-control studies in meta-analysis, the consistent results of prospective cohort studies were considered more accurate, Because of significant heterogeneity after including case-control studies in meta-analysis, the consistent results of prospective cohort studies were considered more accurate, Compared with non-smokers, the overall odd ratio of ED in prospective cohort studies was 1.51(95% CI: 1.34 to 1.71) for current smokers, and it was 1.29 (95% CI: 1.07 to 1.47) for former smokers. Evidence of publication bias was not found. Conclusion: Evidence from epidemiological studies suggests that smoking, especially current smoking, may significantly increase the risk of ED

Suggested Citation

  • Shiyi Cao & Xiaoxu Yin & Yunxia Wang & Hongfeng Zhou & Fujian Song & Zuxun Lu, 2013. "Smoking and Risk of Erectile Dysfunction: Systematic Review of Observational Studies with Meta-Analysis," PLOS ONE, Public Library of Science, vol. 8(4), pages 1-6, April.
    • Handle: RePEc:plo:pone00:0060443
    DOI: 10.1371/journal.pone.0060443
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060443
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0060443&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0060443?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. María Fernanda Valderrama Rodríguez & Laura C. Sánchez-Sánchez & José Manuel García-Montes & Cristina Petisco-Rodríguez, 2023. "A Scoping Review of the Influence of Mindfulness on Men’s Sexual Activity," IJERPH, MDPI, vol. 20(4), pages 1-17, February.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0060443. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.