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Influence of Sinogram Affirmed Iterative Reconstruction of CT Data on Image Noise Characteristics and Low-Contrast Detectability: An Objective Approach

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  • Christian von Falck
  • Vesela Bratanova
  • Thomas Rodt
  • Bernhard Meyer
  • Stephan Waldeck
  • Frank Wacker
  • Hoen-oh Shin

Abstract

Objectives: To utilize a novel objective approach combining a software phantom and an image quality metric to systematically evaluate the influence of sinogram affirmed iterative reconstruction (SAFIRE) of multidetector computed tomography (MDCT) data on image noise characteristics and low-contrast detectability (LCD). Materials and Methods: A low-contrast and a high-contrast phantom were examined on a 128-slice scanner at different dose levels. The datasets were reconstructed using filtered back projection (FBP) and SAFIRE and virtual low-contrast lesions (-20HU) were inserted. LCD was evaluated using the multiscale structural similarity index (MS-SIM*). Image noise texture and spatial resolution were objectively evaluated. Results: The use of SAFIRE led to an improvement of LCD for all dose levels and lesions sizes. The relative improvement of LCD was inversely related to the dose level, declining from 208%(±37%), 259%(±30%) and 309%(±35%) at 25mAs to 106%(±6%), 119%(±9%) and 123%(±8%) at 200mAs for SAFIRE filter strengths of 1, 3 and 5 (p

Suggested Citation

  • Christian von Falck & Vesela Bratanova & Thomas Rodt & Bernhard Meyer & Stephan Waldeck & Frank Wacker & Hoen-oh Shin, 2013. "Influence of Sinogram Affirmed Iterative Reconstruction of CT Data on Image Noise Characteristics and Low-Contrast Detectability: An Objective Approach," PLOS ONE, Public Library of Science, vol. 8(2), pages 1-10, February.
    • Handle: RePEc:plo:pone00:0056875
    DOI: 10.1371/journal.pone.0056875
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