Author
Listed:
- Andreas Beyerlein
- Ina Nehring
- Peter Rzehak
- Joachim Heinrich
- Manfred J Müller
- Sandra Plachta-Danielzik
- Martin Wabitsch
- Melanie Weck
- Hermann Brenner
- Dietrich Rothenbacher
- Rüdiger von Kries
Abstract
Introduction: Previous studies suggested potential priming effects of gestational weight gain (GWG) on offspring’s body composition in later life. However, consistency of these effects in normal weight, overweight and obese mothers is less clear. Methods: We combined the individual data of three German cohorts and assessed associations of total and excessive GWG (as defined by criteria of the Institute of Medicine) with offspring’s mean body mass index (BMI) standard deviation scores (SDS) and overweight at the age of 5–6 years (total: n = 6,254). Quantile regression was used to examine potentially different effects on different parts of the BMI SDS distribution. All models were adjusted for birth weight, maternal age and maternal smoking during pregnancy and stratified by maternal pre-pregnancy weight status. Results: In adjusted models, positive associations of total and excessive GWG with mean BMI SDS and overweight were observed only in children of non- overweight mothers. For example, excessive GWG was associated with a mean increase of 0.08 (95% CI: 0.01, 0.15) units of BMI SDS (0.13 (0.02, 0.24) kg/m2 of ‘real’ BMI) in children of normal-weight mothers. The effects of total and excessive GWG on BMI SDS increased for higher- BMI children of normal-weight mothers. Discussion: Increased GWG is likely to be associated with overweight in offspring of non-overweight mothers.
Suggested Citation
Andreas Beyerlein & Ina Nehring & Peter Rzehak & Joachim Heinrich & Manfred J Müller & Sandra Plachta-Danielzik & Martin Wabitsch & Melanie Weck & Hermann Brenner & Dietrich Rothenbacher & Rüdiger von, 2012.
"Gestational Weight Gain and Body Mass Index in Children: Results from Three German Cohort Studies,"
PLOS ONE, Public Library of Science, vol. 7(3), pages 1-6, March.
Handle:
RePEc:plo:pone00:0033205
DOI: 10.1371/journal.pone.0033205
Download full text from publisher
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0033205. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
We have no bibliographic references for this item. You can help adding them by using this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .
Please note that corrections may take a couple of weeks to filter through
the various RePEc services.