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Age Correction in Dementia – Matching to a Healthy Brain

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  • Juergen Dukart
  • Matthias L Schroeter
  • Karsten Mueller
  • The Alzheimer's Disease Neuroimaging Initiative

Abstract

In recent research, many univariate and multivariate approaches have been proposed to improve automatic classification of various dementia syndromes using imaging data. Some of these methods do not provide the possibility to integrate possible confounding variables like age into the statistical evaluation. A similar problem sometimes exists in clinical studies, as it is not always possible to match different clinical groups to each other in all confounding variables, like for example, early-onset (age

Suggested Citation

  • Juergen Dukart & Matthias L Schroeter & Karsten Mueller & The Alzheimer's Disease Neuroimaging Initiative, 2011. "Age Correction in Dementia – Matching to a Healthy Brain," PLOS ONE, Public Library of Science, vol. 6(7), pages 1-9, July.
    • Handle: RePEc:plo:pone00:0022193
    DOI: 10.1371/journal.pone.0022193
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