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Monte Carlo Simulation of Bony Heterogeneity Effects on Dose Profile for Small Irradiation Field in Radiotherapy

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  • Simone C Cardoso
  • Victor Gabriel L Alves
  • Luiz Antonio R da Rosa
  • Luciana T Campos
  • Delano V S Batista
  • Alessandro Facure

Abstract

In the radiotherapy treatment planning of a lesion located in the head region with small field radiation beams, the heterogeneity corrections play an important role. In this work, we investigated the influence of a bony heterogeneity on dose profile inside a soft tissue phantom containing a bony material. PDD curves were obtained by simulation using the Monte Carlo code EGSnrc and employing Eclipse® treatment planning system algorithms (Batho, Modified Batho, Equivalent TAR and Anisotropic Analytic Algorithm) for a 15 MV photon beam and field sizes of 2×2 and 10×10 cm2. The Equivalent TAR method exhibited better agreement with Monte Carlo simulations for the 2×2 cm2 field size. The magnitude of the effect on PDD due to the bony heterogeneity for 1×1, 2×2 and 10×10 cm2 field sizes increases to 10, 5 and 3%, respectively.

Suggested Citation

  • Simone C Cardoso & Victor Gabriel L Alves & Luiz Antonio R da Rosa & Luciana T Campos & Delano V S Batista & Alessandro Facure, 2010. "Monte Carlo Simulation of Bony Heterogeneity Effects on Dose Profile for Small Irradiation Field in Radiotherapy," PLOS ONE, Public Library of Science, vol. 5(5), pages 1-5, May.
  • Handle: RePEc:plo:pone00:0010466
    DOI: 10.1371/journal.pone.0010466
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