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Assessing Health-Related Quality of life and socioeconomic impacts in low-endemic schistosomiasis: A study from Rural China

Author

Listed:
  • Fei Hu
  • Jun Ge
  • Yifeng Li
  • Zhihong Gong
  • Huiqun Xie
  • Jun Wu
  • Zhuo Wang
  • Sheng Ding

Abstract

To describe and compare health-related quality of life (HRQL) across disease stages (advanced schistosomiasis [AS], schistosomiasis-induced liver fibrosis [SLF], and healthy controls [HP]) in a low-endemic setting, and to explore associations between HRQL and socioeconomic/geographic factors. The findings aim to inform targeted interventions and policies at specific disease stages. A cross-sectional study was conducted in a schistosomiasis-endemic county in Jiangxi Province, China. A total of 2,652 participants, including 884 each in the AS, SLF, and healthy population (HP) groups, were enrolled. HRQL was assessed using the validated Chinese version of the SF-36 questionnaire. Socioeconomic variables (per-capita disposable income of rural households [P-DIRH], per-capita gross domestic product [P-GDP]) and geographic variables (type of schistosomiasis endemic area, endemic status) were analyzed. Non-parametric tests and multivariate linear regression (SPSS 27.0) were employed for statistical analyses. It was observed that the HRQL scores showed a gradually increasing trend (AS

Suggested Citation

  • Fei Hu & Jun Ge & Yifeng Li & Zhihong Gong & Huiqun Xie & Jun Wu & Zhuo Wang & Sheng Ding, 2026. "Assessing Health-Related Quality of life and socioeconomic impacts in low-endemic schistosomiasis: A study from Rural China," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 20(7), pages 1-16, July.
    • Handle: RePEc:plo:pntd00:0014544
    DOI: 10.1371/journal.pntd.0014544
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