IDEAS home Printed from https://ideas.repec.org/a/plo/pmed00/1005223.html

Association between nirsevimab coverage and pediatric emergency department visits for bronchiolitis in 12 European countries: An interrupted time-series analysis

Author

Listed:
  • Léa Lenglart
  • Luigi Titomanlio
  • Ilaria Alberti
  • Laura Almeida
  • Camille Aupiais
  • Esra Akyüz Özkan
  • Michael Barrett
  • Romain Basmaci
  • Ahmet Birbilen
  • Dorine Borensztajn
  • Catarina Braz Schönenberger
  • Silvia Bressan
  • Danilo Buonsenso
  • Teresa Campos
  • Susana Castanhinha
  • Antonio Chiaretti
  • Gemma Claret
  • Francesca De Zan
  • Sheena Durnin
  • Laszlo Fodor
  • Borja Gomez
  • Susanne Greber-Platzer
  • Romain Guedj
  • Alexander Huege
  • Fiona Leonard
  • Ian K Maconochie
  • Robin Marlow
  • Gregorio Milani
  • Miguel Angel Molina Gutierrez
  • Anna Maria Musolino
  • Rianne Oostenbrink
  • Zanda Pucuka
  • Simon Rivière
  • Damian Roland
  • Malin Ryd Rinder
  • Maria Chiara Supino
  • Ozlem Teksam
  • Victoria Trenchs
  • Zaba Valtuille Liebert
  • Bento Vanda
  • Sanne Vrijlandt
  • Naim Ouldali
  • Ruud G Nijman
  • the EPISODES Study Group

Abstract

Background: Nirsevimab was introduced to prevent Respiratory Syncytial Virus (RSV) bronchiolitis in infants. Despite its proven effectiveness and similar guidelines across Europe, bronchiolitis reduction varied across Europe. This study explored whether nirsevimab coverage among targeted populations (born in- and out-of-season) was associated to this variability. Methods and findings: We used routinely collected data from 27 pediatric emergency departments across 12 European countries (01/2018–03/2024). All bronchiolitis cases aged

Suggested Citation

  • Léa Lenglart & Luigi Titomanlio & Ilaria Alberti & Laura Almeida & Camille Aupiais & Esra Akyüz Özkan & Michael Barrett & Romain Basmaci & Ahmet Birbilen & Dorine Borensztajn & Catarina Braz Schönenbe, 2026. "Association between nirsevimab coverage and pediatric emergency department visits for bronchiolitis in 12 European countries: An interrupted time-series analysis," PLOS Medicine, Public Library of Science, vol. 23(9), pages 1-17, September.
    • Handle: RePEc:plo:pmed00:1005223
    DOI: 10.1371/journal.pmed.1005223
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1005223
    Download Restriction: no
    File URL: https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1005223&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pmed.1005223?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pmed00:1005223. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosmedicine (email available below). General contact details of provider: https://journals.plos.org/plosmedicine/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.