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Risk Stratification by Self-Measured Home Blood Pressure across Categories of Conventional Blood Pressure: A Participant-Level Meta-Analysis

Author

Listed:
  • Kei Asayama
  • Lutgarde Thijs
  • Jana Brguljan-Hitij
  • Teemu J Niiranen
  • Atsushi Hozawa
  • José Boggia
  • Lucas S Aparicio
  • Azusa Hara
  • Jouni K Johansson
  • Takayoshi Ohkubo
  • Christophe Tzourio
  • George S Stergiou
  • Edgardo Sandoya
  • Ichiro Tsuji
  • Antti M Jula
  • Yutaka Imai
  • Jan A Staessen
  • for the International Database of Home Blood Pressure in Relation to Cardiovascular Outcome (IDHOCO) investigators

Abstract

: Jan Staessen and colleagues compare the risk of cardiovascular, cardiac, or cerebrovascular events in patients with elevated office blood pressure vs. self-measured home blood pressure. Background: The Global Burden of Diseases Study 2010 reported that hypertension is worldwide the leading risk factor for cardiovascular disease, causing 9.4 million deaths annually. We examined to what extent self-measurement of home blood pressure (HBP) refines risk stratification across increasing categories of conventional blood pressure (CBP). Methods and Findings: This meta-analysis included 5,008 individuals randomly recruited from five populations (56.6% women; mean age, 57.1 y). All were not treated with antihypertensive drugs. In multivariable analyses, hazard ratios (HRs) associated with 10-mm Hg increases in systolic HBP were computed across CBP categories, using the following systolic/diastolic CBP thresholds (in mm Hg): optimal,

Suggested Citation

  • Kei Asayama & Lutgarde Thijs & Jana Brguljan-Hitij & Teemu J Niiranen & Atsushi Hozawa & José Boggia & Lucas S Aparicio & Azusa Hara & Jouni K Johansson & Takayoshi Ohkubo & Christophe Tzourio & Georg, 2014. "Risk Stratification by Self-Measured Home Blood Pressure across Categories of Conventional Blood Pressure: A Participant-Level Meta-Analysis," PLOS Medicine, Public Library of Science, vol. 11(1), pages 1-16, January.
    • Handle: RePEc:plo:pmed00:1001591
    DOI: 10.1371/journal.pmed.1001591
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