Advancing the safe motherhood initiative: A qualitative and sentiment analysis of local physician’s perspectives on antibiotic self-medication during pregnancy in a low- and middle-income country

Although the Safe Motherhood Initiative is currently a global priority, the implications of maternal self-medication for meeting Safe Motherhood and Sustainable Development Goal 3 objectives in low- and middle-income countries has yet to be addressed. Although local medical doctors are an influential stakeholder group, able to determine health policy, how they view and feel about the problem of antimicrobial self-medication during pregnancy is not well understood. Thus, this study explores physicians’ views and sentiments regarding antibiotic self-medication in pregnant women from a West African country. We used mixed qualitative and quantitative analytic approaches. Semi-structured interviews were conducted with 25 medical doctors working in three tertiary hospitals. Thematic analysis was employed to identify key perspectives, while sentiment analysis was used to determine the emotional tone, based on an open-source pre-trained machine learning model for natural language processing. Several checks for methodological rigour were performed, including reviewing records of over 800 email conversations, and conducting respondent validation. Seven distinct themes emerged depicting views on antimicrobial treatment (e.g., easy availability of antibiotics), patient behaviour (e.g., use of medicinal herbs) and policy guidelines on antibiotics stewardship (lack of clear protocols). The prevailing sentiment portrayed a predominantly neutral demeanour towards antibiotic self-medication during pregnancy (χ2 (1, N = 1484) = 1314.858, p