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Implementation of a goal-directed Care Bundle for intracerebral hemorrhage: Results of embedded process evaluation in the INTERACT3 trial

Author

Listed:
  • Menglu Ouyang
  • Anila Anjum
  • Francisca Gonzalez Mc Cawley
  • Mohammad Wasay
  • Lu Ma
  • Xin Hu
  • Xiaoying Chen
  • Alejandra Malavera
  • Xi Li
  • Paula Muñoz Venturelli
  • H Asita de Silva
  • Nguyen Huy Thang
  • Kolawole W Wahab
  • Jeyaraj D Pandian
  • Octavio M Pontes-Neto
  • Carlos Abanto
  • Venessa Cano-Nigenda
  • Antonio Arauz
  • Chao You
  • Stephen Jan
  • Lili Song
  • Craig S Anderson
  • Hueiming Liu
  • for the INTERACT3 Investigators

Abstract

The third, stepped-wedge, cluster-randomized, Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT3), has shown that a goal-directed multi-faceted Care Bundle incorporating protocols for the management of physiological variables was safe and effective for improving functional recovery in a broad range of patients with acute intracerebral hemorrhage (ICH). The INTERACT3 Care Bundle included time- and target-based protocols for the management of early intensive lowering of systolic blood pressure (SBP, target

Suggested Citation

  • Menglu Ouyang & Anila Anjum & Francisca Gonzalez Mc Cawley & Mohammad Wasay & Lu Ma & Xin Hu & Xiaoying Chen & Alejandra Malavera & Xi Li & Paula Muñoz Venturelli & H Asita de Silva & Nguyen Huy Thang, 2024. "Implementation of a goal-directed Care Bundle for intracerebral hemorrhage: Results of embedded process evaluation in the INTERACT3 trial," PLOS Global Public Health, Public Library of Science, vol. 4(12), pages 1-14, December.
    • Handle: RePEc:plo:pgph00:0003711
    DOI: 10.1371/journal.pgph.0003711
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