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The impact of mind-body internet and mobile-based interventions on fatigue in adults living with chronic physical conditions: A systematic review and meta-analysis of randomized controlled trials

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Listed:
  • Serena Isley
  • Emily Johnson
  • Shaina Corrick
  • Ashley Hyde
  • Ben Vandermeer
  • Naomi Dolgoy
  • Nathanael Tabert
  • Edith Pituskin
  • Puneeta Tandon

Abstract

Chronic physical conditions (CPCs) are conditions that persist for long periods and may not have a cure. Fatigue is a common symptom experienced by people living with CPCs. Mind-body internet and mobile-based interventions (IMIs) offer an accessible management strategy. The objective of this review was to assess the impact of mind-body IMIs on fatigue symptoms in adults with CPCs. Six databases were searched from inception to July 2024. Inclusion required randomized controlled trials (RCTs) of mind-body IMIs in adults (≥ 18) with CPCs that assessed fatigue pre-and post-intervention using self-report questionnaires. The primary outcome was the standardized mean fatigue change scores (Hedges’ g). Sub-group analyses were conducted on CPC type, mind-body technique, fatigue questionnaire, and personnel support level. Meta-regression was performed on IMI length and age. Study quality was assessed using the Cochrane Risk of Bias 2.0 tool. The search retrieved 5239 studies. Seventeen studies met inclusion criteria: 47% neurological (n = 8), 29% cancer (n = 5), and 24% autoimmune (n = 4). Seven studies (41%) included cognitive behavioural therapy (CBT), seven used CBT combined with non-CBT techniques, and three employed non-CBT techniques. Mind-body IMIs led to significant reductions in fatigue (SMD = -0.74 [-1.09, -0.39]; p

Suggested Citation

  • Serena Isley & Emily Johnson & Shaina Corrick & Ashley Hyde & Ben Vandermeer & Naomi Dolgoy & Nathanael Tabert & Edith Pituskin & Puneeta Tandon, 2025. "The impact of mind-body internet and mobile-based interventions on fatigue in adults living with chronic physical conditions: A systematic review and meta-analysis of randomized controlled trials," PLOS Digital Health, Public Library of Science, vol. 4(6), pages 1-18, June.
    • Handle: RePEc:plo:pdig00:0000878
    DOI: 10.1371/journal.pdig.0000878
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    References listed on IDEAS

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    1. Rolla Mira & Tim Newton & Wael Sabbah, 2022. "Inequalities in the progress of multiple chronic conditions: A systematic review of longitudinal studies," PLOS ONE, Public Library of Science, vol. 17(2), pages 1-17, February.
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