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Large benefits to youth-focused HIV treatment-as-prevention efforts in generalized heterosexual populations: An agent-based simulation model

Author

Listed:
  • John E Mittler
  • James T Murphy
  • Sarah E Stansfield
  • Kathryn Peebles
  • Geoffrey S Gottlieb
  • Neil F Abernethy
  • Molly C Reid
  • Steven M Goodreau
  • Joshua T Herbeck

Abstract

Predominantly heterosexual HIV-1 epidemics like those in sub-Saharan Africa continue to have high HIV incidence in young people. We used a stochastic, agent-based model for age-disparate networks to test the hypothesis that focusing uptake and retention of ART among youth could enhance the efficiency of treatment as prevention (TasP) campaigns. We used the model to identify strategies that reduce incidence to negligible levels (i.e.,

Suggested Citation

  • John E Mittler & James T Murphy & Sarah E Stansfield & Kathryn Peebles & Geoffrey S Gottlieb & Neil F Abernethy & Molly C Reid & Steven M Goodreau & Joshua T Herbeck, 2019. "Large benefits to youth-focused HIV treatment-as-prevention efforts in generalized heterosexual populations: An agent-based simulation model," PLOS Computational Biology, Public Library of Science, vol. 15(12), pages 1-28, December.
    • Handle: RePEc:plo:pcbi00:1007561
    DOI: 10.1371/journal.pcbi.1007561
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