IDEAS home Printed from https://ideas.repec.org/a/pkp/tijobi/v1y2012i1p21-27id1492.html
   My bibliography  Save this article

Effects of Crude Extract of Ageratum Conyzoides, Moringa Oleifera and Zanthoxylum Zanthoxyloides on Serum Lipid Profile in Albino Rats

Author

Listed:
  • OYEWOLE O.I
  • ADEBAYO A.G
  • OGUNSAKIN S.M

Abstract

Ageratum conyzoides, Moringa oleifera and Zanthoxylum zanthoxyloides are among medicinal plants commonly used in African folk medicine as remedies for the treatments of high blood pressure and heart related diseases. This study was carried out to compare the effects of Ageratum conyzoides, Moringa oleifera and Zanthoxylum zanthoxyloides extracts on serum lipid profile in albino rats. Thirty five albino rats were grouped into seven each containing five rats. Control rats (Group 1) received distilled water while test groups (2-7) were administered the extracts at two dose levels (200mg/kg bw and 500mg/kg bw) for 14 days. Results indicated that Moringa oleifera and Zanthoxylum zanthoxyloides extracts caused significant reduction in the concentrations of serum total cholesterol, triacylglycerol and LDL-cholesterol with Moringa oleifera having the most significant effect. There was also a significant increase in HDL-cholesterol concentration in rats administered Zanthoxylum zanthoxyloides compared with the control. Treatment of rats with Ageratum conyzoides had no effects on lipid metabolism as there was no significant changes in lipid profile of rats treated with this extract compared with the control. This result implies that Moringa oleifera and Zanthoxylum zanthoxyloides might be useful in the treatment of hypertension and other cardiovascular diseases arising from hyperlipidemia.

Suggested Citation

  • Oyewole O.I & Adebayo A.G & Ogunsakin S.M, 2012. "Effects of Crude Extract of Ageratum Conyzoides, Moringa Oleifera and Zanthoxylum Zanthoxyloides on Serum Lipid Profile in Albino Rats," The International Journal of Biotechnology, Conscientia Beam, vol. 1(1), pages 21-27.
    • Handle: RePEc:pkp:tijobi:v:1:y:2012:i:1:p:21-27:id:1492
    as

    Download full text from publisher

    File URL: https://archive.conscientiabeam.com/index.php/57/article/view/1492/2081
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:pkp:tijobi:v:1:y:2012:i:1:p:21-27:id:1492. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Dim Michael (email available below). General contact details of provider: https://archive.conscientiabeam.com/index.php/57/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.