IDEAS home Printed from https://ideas.repec.org/a/pkp/ijomah/v2y2015i1p15-24id2236.html
   My bibliography  Save this article

Effect of Dietary Supplementation with Cyphostemma Digitatum on Serum Lipid Profile and Liver Enzymes in Hyperlipidemic Subjects

Author

Listed:
  • Mohammed A Al-Duais
  • Qais A Nogaim
  • Yahya S Al-Awthan
  • Aisha Al-Dherasi

Abstract

Aims: To examine the effects of the administration of CD on lipid metabolism and liver enzymes in hyperlipidemic subjects. Study design: 20 subjects were divided into two groups, each containing ten subjects. Each subject in the 1st group ingested 1g, while the subject in the 2nd group ingested 2g of CD powder as a broth suspension in a single daily dose before lunch during the follow up period of one month. Patients kept their individual diet relatively constant. Methodology: We included 20 hyperlipidemic volunteers (men; age range 20-50 years) of a total of 80 subjects. Blood samples were taken and analyzed for total cholesterol (TC), triglycerides (TG), high density lipoprotein cholesterol (HDL-C), Low density lipoprotein cholesterol (LDL-C), atherogenic index (AI), serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP). Results: The results of the present study show a significant decrease in the levels of TC, LDL-C and TG in 1g and 2g of CD administration groups by 12.6, 24.1, 17.1% and 19.9, 25.5 23.4% respectively while the level of HDL-C was significantly increased by 45.6 and 32.5% in 1g and 2g respectively. The atherogenic index (AI) was significantly decreased in 1g and 2g groups by and 47.4% and 45.5% respectively. Our results also show that, CD administration in 1g and 2g subjects causes a significant decrease in ALT and AST by 39.2, 32% and 48.5, 33.3% respectively while the level of ALP was non-significantly decreased. Conclusion: dietary supplementation with CD administration decreased serum lipid profile and liver enzymes in hyperlipidemic subjects. Therefore, it may be regarded as a useful therapy for hyperlipidemia and liver disease. However, further studies are required to compare it with other medicinal plants and with lipid lowering drugs. Place and Duration of Study: Department of Chemistry, Ibb University, Yemen, between February to June 2012.

Suggested Citation

  • Mohammed A Al-Duais & Qais A Nogaim & Yahya S Al-Awthan & Aisha Al-Dherasi, 2015. "Effect of Dietary Supplementation with Cyphostemma Digitatum on Serum Lipid Profile and Liver Enzymes in Hyperlipidemic Subjects," International Journal of Medical and Health Sciences Research, Conscientia Beam, vol. 2(1), pages 15-24.
    • Handle: RePEc:pkp:ijomah:v:2:y:2015:i:1:p:15-24:id:2236
    as

    Download full text from publisher

    File URL: https://archive.conscientiabeam.com/index.php/9/article/view/2236/3300
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:pkp:ijomah:v:2:y:2015:i:1:p:15-24:id:2236. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Dim Michael (email available below). General contact details of provider: https://archive.conscientiabeam.com/index.php/9/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.