IDEAS home Printed from https://ideas.repec.org/a/pal/palcom/v12y2025i1d10.1057_s41599-025-04894-w.html
   My bibliography  Save this article

Acquisitions as catalysts for inventor departures in the biotechnology industry

Author

Listed:
  • Luca Verginer

    (Chair of Systems Design at ETH Zürich)

  • Federica Parisi

    (IMT School for Advanced Studies Lucca)

  • Jeroen Lidth de Jeude

    (IMT School for Advanced Studies Lucca)

  • Massimo Riccaboni

    (IMT School for Advanced Studies Lucca
    IUSS University School for Advanced Studies of Pavia)

Abstract

In high-tech industries, where intellectual property is crucial, the acquisition of intangible assets and tacit knowledge of employees is one of the main motivations for Mergers and Acquisitions (M&As). The takeover wave in the biotechnology industry in the 1990s following the molecular biology revolution is a well-known example of how M&As were used to absorb new knowledge. However, after an M&A, it is uncertain whether key R&D employees who embody valuable knowledge and potential future innovations can be retained. Even if not all employees are relevant to the success of the acquisition, inventors are among the most valuable. This is especially true when acquiring an innovative startup. In this paper, we estimate how likely it is that an inventor working for an acquired biotechnology company will leave. Using a difference-in-differences approach with matching for both firms and inventors. We find that inventors affected by acquisitions are 20% more likely to leave the company. Our results contribute to the current debate on acqui-hiring of high-tech startups.

Suggested Citation

  • Luca Verginer & Federica Parisi & Jeroen Lidth de Jeude & Massimo Riccaboni, 2025. "Acquisitions as catalysts for inventor departures in the biotechnology industry," Palgrave Communications, Palgrave Macmillan, vol. 12(1), pages 1-12, December.
  • Handle: RePEc:pal:palcom:v:12:y:2025:i:1:d:10.1057_s41599-025-04894-w
    DOI: 10.1057/s41599-025-04894-w
    as

    Download full text from publisher

    File URL: http://link.springer.com/10.1057/s41599-025-04894-w
    File Function: Abstract
    Download Restriction: Access to full text is restricted to subscribers.

    File URL: https://libkey.io/10.1057/s41599-025-04894-w?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Weiyi Ng & Toby E. Stuart, 2022. "Acquired employees versus hired employees: Retained or turned over?," Strategic Management Journal, Wiley Blackwell, vol. 43(5), pages 1025-1045, May.
    2. Orsenigo, L. & Pammolli, F. & Riccaboni, Massimo, 2001. "Technological change and network dynamics: Lessons from the pharmaceutical industry," Research Policy, Elsevier, vol. 30(3), pages 485-508, March.
    3. Sam Arts & Bruno Cassiman & Juan Carlos Gomez, 2018. "Text matching to measure patent similarity," Strategic Management Journal, Wiley Blackwell, vol. 39(1), pages 62-84, January.
    4. Riccaboni, Massimo & Pammolli, Fabio, 2002. "On firm growth in networks," Research Policy, Elsevier, vol. 31(8-9), pages 1405-1416, December.
    5. Heski Bar-Isaac & Justin P. Johnson & Volker Nocke, 2025. "Acquihiring for Monopsony Power," Management Science, INFORMS, vol. 71(4), pages 3485-3496, April.
    6. Cloodt, Myriam & Hagedoorn, John & Van Kranenburg, Hans, 2006. "Mergers and acquisitions: Their effect on the innovative performance of companies in high-tech industries," Research Policy, Elsevier, vol. 35(5), pages 642-654, June.
    7. Srikanth Paruchuri & Atul Nerkar & Donald C. Hambrick, 2006. "Acquisition Integration and Productivity Losses in the Technical Core: Disruption of Inventors in Acquired Companies," Organization Science, INFORMS, vol. 17(5), pages 545-562, October.
    8. James Heckman, 2013. "Sample selection bias as a specification error," Applied Econometrics, Russian Presidential Academy of National Economy and Public Administration (RANEPA), vol. 31(3), pages 129-137.
    9. Kenneth A. Younge & Tony W. Tong & Lee Fleming, 2015. "How anticipated employee mobility affects acquisition likelihood: Evidence from a natural experiment," Strategic Management Journal, Wiley Blackwell, vol. 36(5), pages 686-708, May.
    10. Wesley M. Cohen & Richard R. Nelson & John P. Walsh, 2000. "Protecting Their Intellectual Assets: Appropriability Conditions and Why U.S. Manufacturing Firms Patent (or Not)," NBER Working Papers 7552, National Bureau of Economic Research, Inc.
    11. Samina Karim & Will Mitchell, 2000. "Path‐dependent and path‐breaking change: reconfiguring business resources following acquisitions in the U.S. medical sector, 1978–1995," Strategic Management Journal, Wiley Blackwell, vol. 21(10‐11), pages 1061-1081, October.
    12. Belén Villalonga & Anita M. McGahan, 2005. "The choice among acquisitions, alliances, and divestitures," Strategic Management Journal, Wiley Blackwell, vol. 26(13), pages 1183-1208, December.
    13. Carayannopoulos, Sofy & Auster, Ellen R., 2010. "External knowledge sourcing in biotechnology through acquisition versus alliance: A KBV approach," Research Policy, Elsevier, vol. 39(2), pages 254-267, March.
    14. Patricia M. Danzon & Andrew Epstein & Sean Nicholson, 2007. "Mergers and acquisitions in the pharmaceutical and biotech industries," Managerial and Decision Economics, John Wiley & Sons, Ltd., vol. 28(4-5), pages 307-328.
    15. Heski Bar-Isaac & Justin P. Johnson & Volker Nocke, 2025. "Acquihiring for Monopsony Power," Management Science, INFORMS, vol. 71(4), pages 3485-3496, April.
    16. David R. King & Dan R. Dalton & Catherine M. Daily & Jeffrey G. Covin, 2004. "Meta‐analyses of post‐acquisition performance: indications of unidentified moderators," Strategic Management Journal, Wiley Blackwell, vol. 25(2), pages 187-200, February.
    17. Gautam Ahuja & Riitta Katila, 2001. "Technological acquisitions and the innovation performance of acquiring firms: a longitudinal study," Strategic Management Journal, Wiley Blackwell, vol. 22(3), pages 197-220, March.
    18. Galdino, Katia M. & Gordon, Janice & King, David R., 2022. "The impact of distance on acquisition performance," European Management Journal, Elsevier, vol. 40(6), pages 857-872.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Luca Verginer & Federica Parisi & Jeroen van Lidth de Jeude & Massimo Riccaboni, 2022. "The Impact of Acquisitions in the Biotechnology Sector on R&D Productivity," Papers 2203.12968, arXiv.org, revised Jan 2024.
    2. Namgyoo K. Park & Monica Youngshin Chun & Jeonghwan Lee, 2019. "How Do Mobility Direction and Human Assets of Mobile Engineers Affect Joint Knowledge Creation after M&As?," Sustainability, MDPI, vol. 11(16), pages 1-21, August.
    3. Schön, Benjamin & Pyka, Andreas, 2013. "The success factors of technology-sourcing through mergers & acquisitions: An intuitive meta-analysis," FZID Discussion Papers 78-2013, University of Hohenheim, Center for Research on Innovation and Services (FZID).
    4. Voss, Philipp S.R., 2022. "Innovation Performance in Healthcare M&A: An Empirical Analysis," Junior Management Science (JUMS), Junior Management Science e. V., vol. 7(4), pages 1164-1192.
    5. Carayannopoulos, Sofy & Auster, Ellen R., 2010. "External knowledge sourcing in biotechnology through acquisition versus alliance: A KBV approach," Research Policy, Elsevier, vol. 39(2), pages 254-267, March.
    6. Arroyabe, M. F. & Grimpe, Christoph & Hussinger, Katrin, 2025. "Safeguarding secrets, shaping acquisitions: Trade secret protection and the role of distance between acquirer and target," ZEW Discussion Papers 25-007, ZEW - Leibniz Centre for European Economic Research.
    7. Mahka Moeen & Will Mitchell, 2020. "How do pre‐entrants to the industry incubation stage choose between alliances and acquisitions for technical capabilities and specialized complementary assets?," Strategic Management Journal, Wiley Blackwell, vol. 41(8), pages 1450-1489, August.
    8. Galina Besstremyannaya & Richard Dasher & Sergei Golovan, 2019. "Growth through acquisition of innovations," Working Papers w0247, Center for Economic and Financial Research (CEFIR).
    9. Chondrakis, George, 2016. "Unique synergies in technology acquisitions," Research Policy, Elsevier, vol. 45(9), pages 1873-1889.
    10. Shuwaikh, Fatima & Dubocage, Emmanuelle, 2022. "Access to the Corporate Investors' Complementary Resources: A Leverage for Innovation in Biotech Venture Capital-Backed Companies," Technological Forecasting and Social Change, Elsevier, vol. 175(C).
    11. Jacob, Jojo & Belderbos, René & Lokshin, Boris, 2023. "Entangled modes: Boundaries to effective international knowledge sourcing through technology alliances and technology-based acquisitions," Technovation, Elsevier, vol. 122(C).
    12. Ralph Siebert & Zhili Tian, 2020. "Dynamic Mergers Effects on R&D Investments and Drug Development across Research Phases in the Pharmaceutical Industry," CESifo Working Paper Series 8303, CESifo.
    13. Strobl, Andreas & Bauer, Florian & Matzler, Kurt, 2020. "The impact of industry-wide and target market environmental hostility on entrepreneurial leadership in mergers and acquisitions," Journal of World Business, Elsevier, vol. 55(2).
    14. Uriel Stettner & Dovev Lavie, 2014. "Ambidexterity under scrutiny: Exploration and exploitation via internal organization, alliances, and acquisitions," Strategic Management Journal, Wiley Blackwell, vol. 35(13), pages 1903-1929, December.
    15. Sears, Joshua B. & Hitt, Michael A., 2023. "Post-acquisition integrative invention and differences in the quality of target and acquirer technological capabilities," Journal of Business Research, Elsevier, vol. 156(C).
    16. Maria Chiara Di Guardo & Kathryn Rudie Harrigan & Elona Marku, 2019. "M&A and diversification strategies: what effect on quality of inventive activity?," Journal of Management & Governance, Springer;Accademia Italiana di Economia Aziendale (AIDEA), vol. 23(3), pages 669-692, September.
    17. Galina Besstremyannaya & Richard Dasher & Sergei Golovan, 2018. "Growth through acquisition of innovations," Working Papers w0247, New Economic School (NES).
    18. Stienstra, Miranda, 2020. "The determinants and performance implications of alliance partner acquisition," Other publications TiSEM 7fdee0c2-d4d2-4f5b-95e3-2, Tilburg University, School of Economics and Management.
    19. Katrin Hussinger, 2012. "Absorptive capacity and post-acquisition inventor productivity," The Journal of Technology Transfer, Springer, vol. 37(4), pages 490-507, August.
    20. James Foreman-Peck & Tom Nicholls, 2013. "SME takeovers as a contributor to regional productivity gaps," Small Business Economics, Springer, vol. 41(2), pages 359-378, August.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:pal:palcom:v:12:y:2025:i:1:d:10.1057_s41599-025-04894-w. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: https://www.nature.com/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.