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Nonparametric incidence estimation from prevalent cohort survival data

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  • Marco Carone
  • Masoud Asgharian
  • Mei-Cheng Wang

Abstract

Incidence is an important epidemiological concept most suitably studied using an incident cohort study. However, data are often collected from the more feasible prevalent cohort study, whereby diseased individuals are recruited through a cross-sectional survey and followed in time. In the absence of temporal trends in survival, we derive an efficient nonparametric estimator of the cumulative incidence based on such data and study its asymptotic properties. Arbitrary calendar time variations in disease incidence are allowed. Age-specific incidence and adjustments for both stratified sampling and temporal variations in survival are also discussed. Simulation results are presented and data from the Canadian Study of Health and Aging are analysed to infer the incidence of dementia in the Canadian elderly population. Copyright 2012, Oxford University Press.

Suggested Citation

  • Marco Carone & Masoud Asgharian & Mei-Cheng Wang, 2012. "Nonparametric incidence estimation from prevalent cohort survival data," Biometrika, Biometrika Trust, vol. 99(3), pages 599-613.
  • Handle: RePEc:oup:biomet:v:99:y:2012:i:3:p:599-613
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    File URL: http://hdl.handle.net/10.1093/biomet/ass017
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    Cited by:

    1. Shi, Jianhua & Ma, Huijuan & Zhou, Yong, 2018. "The nonparametric quantile estimation for length-biased and right-censored data," Statistics & Probability Letters, Elsevier, vol. 134(C), pages 150-158.

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