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Mitochondrial distress call moves to the cytosol to trigger a response to stress

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  • Bradford P. Tremblay
  • Cole M. Haynes

Abstract

Cellular stress can result in dysfunction and disease, and mechanisms exist to combat this. Previously unknown steps have been uncovered in a pathway that signals when mitochondrial organelles are dysfunctional.

Suggested Citation

  • Bradford P. Tremblay & Cole M. Haynes, 2020. "Mitochondrial distress call moves to the cytosol to trigger a response to stress," Nature, Nature, vol. 579(7799), pages 348-349, March.
    • Handle: RePEc:nat:nature:v:579:y:2020:i:7799:d:10.1038_d41586-020-00552-0
    DOI: 10.1038/d41586-020-00552-0
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    Cited by:

    1. Huishou Zhao & Dan Sun & Shan Wang & Yi Liu & Xiaojuan Zhao & Wenqi Tian & Xiuhong Dou & Jilong Liu & Jinyang Xu & Lu Peng & Shiren Sun & Yunlong Xia & Xiaoming Xu & Cheng Wang & Di Wang & Guohong Zha, 2025. "Branched-chain amino acids contribute to diabetic kidney disease progression via PKM2-mediated podocyte metabolic reprogramming and apoptosis," Nature Communications, Nature, vol. 16(1), pages 1-20, December.

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