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Human umbilical cord plasma proteins revitalize hippocampal function in aged mice

Author

Listed:
  • Joseph M. Castellano

    (Stanford University School of Medicine
    Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine)

  • Kira I. Mosher

    (Stanford University School of Medicine
    Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine
    Neuroscience Graduate Program, Stanford University School of Medicine)

  • Rachelle J. Abbey

    (Stanford University School of Medicine
    Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine
    Center for Tissue Regeneration, Repair and Restoration, V.A. Palo Alto Healthcare System)

  • Alisha A. McBride

    (Stanford University School of Medicine
    Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine
    Center for Tissue Regeneration, Repair and Restoration, V.A. Palo Alto Healthcare System)

  • Michelle L. James

    (Stanford University School of Medicine
    Molecular Imaging Program at Stanford, Radiology, Stanford University School of Medicine)

  • Daniela Berdnik

    (Stanford University School of Medicine
    Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine
    Center for Tissue Regeneration, Repair and Restoration, V.A. Palo Alto Healthcare System)

  • Jadon C. Shen

    (Stanford University School of Medicine
    Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine
    Center for Tissue Regeneration, Repair and Restoration, V.A. Palo Alto Healthcare System)

  • Bende Zou

    (AfaSci Research Laboratories)

  • Xinmin S. Xie

    (AfaSci Research Laboratories
    Perioperative and Pain Medicine, Stanford University School of Medicine)

  • Martha Tingle

    (Perioperative and Pain Medicine, Stanford University School of Medicine)

  • Izumi V. Hinkson

    (Stanford University School of Medicine
    Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine
    Center for Tissue Regeneration, Repair and Restoration, V.A. Palo Alto Healthcare System)

  • Martin S. Angst

    (Perioperative and Pain Medicine, Stanford University School of Medicine)

  • Tony Wyss-Coray

    (Stanford University School of Medicine
    Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine
    Neuroscience Graduate Program, Stanford University School of Medicine
    Center for Tissue Regeneration, Repair and Restoration, V.A. Palo Alto Healthcare System)

Abstract

Treatment with plasma of an early developmental stage, human umbilical cord, revitalizes the hippocampus and improves cognitive function in aged mice.

Suggested Citation

  • Joseph M. Castellano & Kira I. Mosher & Rachelle J. Abbey & Alisha A. McBride & Michelle L. James & Daniela Berdnik & Jadon C. Shen & Bende Zou & Xinmin S. Xie & Martha Tingle & Izumi V. Hinkson & Mar, 2017. "Human umbilical cord plasma proteins revitalize hippocampal function in aged mice," Nature, Nature, vol. 544(7651), pages 488-492, April.
    • Handle: RePEc:nat:nature:v:544:y:2017:i:7651:d:10.1038_nature22067
    DOI: 10.1038/nature22067
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