IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v539y2016i7630d10.1038_nature20127.html
   My bibliography  Save this article

A cannabinoid link between mitochondria and memory

Author

Listed:
  • Etienne Hebert-Chatelain

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie
    Université de Moncton)

  • Tifany Desprez

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Román Serrat

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Luigi Bellocchio

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie
    Complutense University)

  • Edgar Soria-Gomez

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Arnau Busquets-Garcia

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Antonio Christian Pagano Zottola

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Anna Delamarre

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Astrid Cannich

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Peggy Vincent

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Marjorie Varilh

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Laurie M. Robin

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Geoffrey Terral

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • M. Dolores García-Fernández

    (IMG Pharma Biotech S.L.
    Faculty of Medicine and Dentistry, University of the Basque Country UPV/EHU)

  • Michelangelo Colavita

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie
    Section of Pharmacology, University of Catania)

  • Wilfrid Mazier

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Filippo Drago

    (Section of Pharmacology, University of Catania)

  • Nagore Puente

    (Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU
    Achucarro Basque Center for Neuroscience, Bizkaia Science and Technology Park)

  • Leire Reguero

    (Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU
    Achucarro Basque Center for Neuroscience, Bizkaia Science and Technology Park)

  • Izaskun Elezgarai

    (Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU
    Achucarro Basque Center for Neuroscience, Bizkaia Science and Technology Park)

  • Jean-William Dupuy

    (Université de Bordeaux, Centre Génomique Fonctionnelle)

  • Daniela Cota

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Maria-Luz Lopez-Rodriguez

    (Complutense University)

  • Gabriel Barreda-Gómez

    (IMG Pharma Biotech S.L.)

  • Federico Massa

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Pedro Grandes

    (Faculty of Medicine and Nursing, University of the Basque Country UPV/EHU
    Achucarro Basque Center for Neuroscience, Bizkaia Science and Technology Park
    University of Victoria)

  • Giovanni Bénard

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

  • Giovanni Marsicano

    (INSERM U1215, NeuroCentre Magendie
    Université de Bordeaux, NeuroCentre Magendie)

Abstract

Cannabinoids affect CB1 receptors on the mitochondrial membranes in the brain, triggering a decrease in downstream cAMP-dependent signalling; this leads to a decrease in brain mitochondrial activity and to cannabinoid-induced amnesia.

Suggested Citation

  • Etienne Hebert-Chatelain & Tifany Desprez & Román Serrat & Luigi Bellocchio & Edgar Soria-Gomez & Arnau Busquets-Garcia & Antonio Christian Pagano Zottola & Anna Delamarre & Astrid Cannich & Peggy Vin, 2016. "A cannabinoid link between mitochondria and memory," Nature, Nature, vol. 539(7630), pages 555-559, November.
    • Handle: RePEc:nat:nature:v:539:y:2016:i:7630:d:10.1038_nature20127
    DOI: 10.1038/nature20127
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature20127
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature20127?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Albert Stuart Reece & Gary Kenneth Hulse, 2023. "Clinical Epigenomic Explanation of the Epidemiology of Cannabinoid Genotoxicity Manifesting as Transgenerational Teratogenesis, Cancerogenesis and Aging Acceleration," IJERPH, MDPI, vol. 20(4), pages 1-24, February.
    2. Albert Stuart Reece & Gary Kenneth Hulse, 2022. "Epidemiology of Δ8THC-Related Carcinogenesis in USA: A Panel Regression and Causal Inferential Study," IJERPH, MDPI, vol. 19(13), pages 1-27, June.
    3. Albert Stuart Reece & Gary Kenneth Hulse, 2022. "Epigenomic and Other Evidence for Cannabis-Induced Aging Contextualized in a Synthetic Epidemiologic Overview of Cannabinoid-Related Teratogenesis and Cannabinoid-Related Carcinogenesis," IJERPH, MDPI, vol. 19(24), pages 1-57, December.
    4. Albert Stuart Reece & Gary Kenneth Hulse, 2022. "State Trends of Cannabis Liberalization as a Causal Driver of Increasing Testicular Cancer Rates across the USA," IJERPH, MDPI, vol. 19(19), pages 1-37, October.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:539:y:2016:i:7630:d:10.1038_nature20127. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.