IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v523y2015i7560d10.1038_nature14562.html
   My bibliography  Save this article

A noisy linear map underlies oscillations in cell size and gene expression in bacteria

Author

Listed:
  • Yu Tanouchi

    (Duke University)

  • Anand Pai

    (Duke University)

  • Heungwon Park

    (Duke University
    Duke University)

  • Shuqiang Huang

    (Duke University)

  • Rumen Stamatov

    (Computational Biology and Bioinformatics, Duke University)

  • Nicolas E. Buchler

    (Duke University
    Duke University
    Center for Genomic and Computational Biology, Duke University)

  • Lingchong You

    (Duke University
    Center for Genomic and Computational Biology, Duke University)

Abstract

Quantification of single-cell growth over long periods of time in E. coli shows transient oscillations in cell size, with periods stretching across more than ten generations; a noisy negative feedback on cell-size control is proposed in which cells with a small initial size tend to divide later than cells with a large initial size with implications for the genetic and physiological processes required.

Suggested Citation

  • Yu Tanouchi & Anand Pai & Heungwon Park & Shuqiang Huang & Rumen Stamatov & Nicolas E. Buchler & Lingchong You, 2015. "A noisy linear map underlies oscillations in cell size and gene expression in bacteria," Nature, Nature, vol. 523(7560), pages 357-360, July.
    • Handle: RePEc:nat:nature:v:523:y:2015:i:7560:d:10.1038_nature14562
    DOI: 10.1038/nature14562
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature14562
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature14562?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Diederik S. Laman Trip & Théo Maire & Hyun Youk, 2022. "Slowest possible replicative life at frigid temperatures for yeast," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
    2. Nieto, César & Vargas, Cesar & Singh, Abhyudai, 2023. "Statistical properties of dynamical models underlying cell size homeostasis," OSF Preprints ea6yx, Center for Open Science.
    3. Harsh Vashistha & Joanna Jammal-Touma & Kulveer Singh & Yitzhak Rabin & Hanna Salman, 2023. "Bacterial cell-size changes resulting from altering the relative expression of Min proteins," Nature Communications, Nature, vol. 14(1), pages 1-11, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:523:y:2015:i:7560:d:10.1038_nature14562. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.