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Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

Author

Listed:
  • Konstantinos Palikaras

    (Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas
    University of Crete)

  • Eirini Lionaki

    (Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas)

  • Nektarios Tavernarakis

    (Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology - Hellas
    Faculty of Medicine, University of Crete)

Abstract

Mitophagy, a selective type of autophagy targeting mitochondria for degradation, interfaces with mitochondrial biogenesis to regulate mitochondrial content and longevity in Caenorhabditis elegans.

Suggested Citation

  • Konstantinos Palikaras & Eirini Lionaki & Nektarios Tavernarakis, 2015. "Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans," Nature, Nature, vol. 521(7553), pages 525-528, May.
    • Handle: RePEc:nat:nature:v:521:y:2015:i:7553:d:10.1038_nature14300
    DOI: 10.1038/nature14300
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    Cited by:

    1. Michael J. Munson & Benan J. Mathai & Matthew Yoke Wui Ng & Laura Trachsel-Moncho & Laura R. Ballina & Sebastian W. Schultz & Yahyah Aman & Alf H. Lystad & Sakshi Singh & Sachin Singh & Jørgen Wesche , 2021. "GAK and PRKCD are positive regulators of PRKN-independent mitophagy," Nature Communications, Nature, vol. 12(1), pages 1-22, December.
    2. Michael Webb & Jyoti Malhotra & Chui-Se Tham & Matthew Goddeeris & Douglas W McMillin & Effie Tozzo, 2017. "A Novel Mitophagy Assay for Skeletal Myotubes," Open Access Journal of Neurology & Neurosurgery, Juniper Publishers Inc., vol. 4(4), pages 79-86, July.
    3. Eirini Lionaki & Ilias Gkikas & Ioanna Daskalaki & Maria-Konstantina Ioannidi & Maria I. Klapa & Nektarios Tavernarakis, 2022. "Mitochondrial protein import determines lifespan through metabolic reprogramming and de novo serine biosynthesis," Nature Communications, Nature, vol. 13(1), pages 1-16, December.

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