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Disarming Wnt

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  • Roel Nusse

    (Roel Nusse is at the Howard Hughes Medical Institute, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305-5458, USA.)

Abstract

The secreted enzyme Notum has been found to inhibit the Wnt signalling pathway through removal of a lipid that is linked to the Wnt protein and that is required for activation of Wnt receptor proteins. See Article p.187

Suggested Citation

  • Roel Nusse, 2015. "Disarming Wnt," Nature, Nature, vol. 519(7542), pages 163-164, March.
    • Handle: RePEc:nat:nature:v:519:y:2015:i:7542:d:10.1038_nature14208
    DOI: 10.1038/nature14208
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