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Non-optimal codon usage is a mechanism to achieve circadian clock conditionality

Author

Listed:
  • Yao Xu

    (Vanderbilt University)

  • Peijun Ma

    (Vanderbilt University)

  • Premal Shah

    (University of Pennsylvania)

  • Antonis Rokas

    (Vanderbilt University)

  • Yi Liu

    (The University of Texas Southwestern Medical Center)

  • Carl Hirschie Johnson

    (Vanderbilt University)

Abstract

Central circadian proteins in cyanobacteria unexpectedly use non-optimal codons, and optimizing their codes is shown to cause a change in an adaptive response to environmental conditions.

Suggested Citation

  • Yao Xu & Peijun Ma & Premal Shah & Antonis Rokas & Yi Liu & Carl Hirschie Johnson, 2013. "Non-optimal codon usage is a mechanism to achieve circadian clock conditionality," Nature, Nature, vol. 495(7439), pages 116-120, March.
    • Handle: RePEc:nat:nature:v:495:y:2013:i:7439:d:10.1038_nature11942
    DOI: 10.1038/nature11942
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    Cited by:

    1. Rachele Rossi & Mingyan Fang & Lin Zhu & Chongyi Jiang & Cong Yu & Cristina Flesia & Chao Nie & Wenyan Li & Alessandra Ferlini, 2022. "Calculating and comparing codon usage values in rare disease genes highlights codon clustering with disease-and tissue- specific hierarchy," PLOS ONE, Public Library of Science, vol. 17(3), pages 1-25, March.

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