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The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection

Author

Listed:
  • Thomas Costelloe

    (Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands)

  • Raphaël Louge

    (Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7258
    Aix-Marseille University, Unité Mixte de Recherche 7258)

  • Nozomi Tomimatsu

    (University of Texas Southwestern Medical Center, 2201 Inwood Road, NC7.214E, Dallas, Texas 75390, USA)

  • Bipasha Mukherjee

    (University of Texas Southwestern Medical Center, 2201 Inwood Road, NC7.214E, Dallas, Texas 75390, USA)

  • Emmanuelle Martini

    (CEA-DSV-Institut de Radiobiologie Cellulaire et Moléculaire)

  • Basheer Khadaroo

    (Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7258
    Aix-Marseille University, Unité Mixte de Recherche 7258)

  • Kenny Dubois

    (Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7258
    Aix-Marseille University, Unité Mixte de Recherche 7258)

  • Wouter W. Wiegant

    (Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands)

  • Agnès Thierry

    (Institut Pasteur, Unité de Génétique Moléculaire des Levures, Centre National de la Recherche Scientifique and University Pierre and Marie Curie-Paris, 25 rue du Docteur Roux, F75724 Paris Cedex 15, France)

  • Sandeep Burma

    (University of Texas Southwestern Medical Center, 2201 Inwood Road, NC7.214E, Dallas, Texas 75390, USA)

  • Haico van Attikum

    (Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands)

  • Bertrand Llorente

    (Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7258
    Aix-Marseille University, Unité Mixte de Recherche 7258)

Abstract

Fun30 and SMARCAD1 are identified as chromatin remodellers that promote DNA end resection during DNA repair and preserve genome stability in yeast and humans, respectively.

Suggested Citation

  • Thomas Costelloe & Raphaël Louge & Nozomi Tomimatsu & Bipasha Mukherjee & Emmanuelle Martini & Basheer Khadaroo & Kenny Dubois & Wouter W. Wiegant & Agnès Thierry & Sandeep Burma & Haico van Attikum &, 2012. "The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection," Nature, Nature, vol. 489(7417), pages 581-584, September.
    • Handle: RePEc:nat:nature:v:489:y:2012:i:7417:d:10.1038_nature11353
    DOI: 10.1038/nature11353
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